Risks of Muscle Atrophy in Patients with Malignant Lymphoma after Autologous Stem Cell Transplantation.

hematologic malignancies hematopoietic stem cell transplantation muscle atrophy sarcopenia skeletal muscle index

Journal

Physical therapy research
ISSN: 2189-8448
Titre abrégé: Phys Ther Res
Pays: Japan
ID NLM: 101700769

Informations de publication

Date de publication:
2021
Historique:
received: 18 04 2020
accepted: 25 09 2020
entrez: 13 5 2021
pubmed: 14 5 2021
medline: 14 5 2021
Statut: epublish

Résumé

Muscle atrophy is associated with autologous stem cell transplantation (ASCT)-related outcomes in patients with malignant lymphoma (ML). However, the impact of ASCT on muscle mass remains unclear in patients with ML. The aims of this study were to investigate changes in muscle mass and risk profiles for muscle atrophy after ASCT. We enrolled 40 patients with refractory ML (age 58 [20-74] years, female/male 16/24, body mass index (BMI) 21.1 kg/m Independent factors associated with a severe decrease rate of change in PMI were evaluated by decision-tree analysis, respectively. PMI was significantly decreased after ASCT (4.61 vs. 4.55 cm We demonstrated that muscle mass decreased after ASCT in patients with ML. Patients who received MCEC and patients with low BMI were at risk for a decrease in muscle mass.

Identifiants

pubmed: 33981529
doi: 10.1298/ptr.E10041
pmc: PMC8111411
doi:

Types de publication

Journal Article

Langues

eng

Pagination

69-76

Informations de copyright

2021, JAPANESE PHYSICAL THERAPY ASSOCIATION.

Déclaration de conflit d'intérêts

There is no conflict of interest to disclose.

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Auteurs

Keisuke Hirota (K)

Division of Rehabilitation, Kurume University Hospital, Kurume, Japan.

Hiroo Matsuse (H)

Department of Orthopedics, Kurume University School of Medicine, Kurume, Japan.

Shunji Koya (S)

Division of Rehabilitation, Kurume University Hospital, Kurume, Japan.

Ryuki Hashida (R)

Department of Orthopedics, Kurume University School of Medicine, Kurume, Japan.

Masafumi Bekki (M)

Department of Orthopedics, Kurume University School of Medicine, Kurume, Japan.

Yoko Yanaga (Y)

Department of Nursing, Kurume University Hospital, Kurume, Japan.

Kiyoko Johzaki (K)

Department of Nursing, Kurume University Hospital, Kurume, Japan.

Mami Tomino (M)

Department of Nursing, Kurume University Hospital, Kurume, Japan.

Fumihiko Mouri (F)

Division of Hematology and Oncology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan.

Satoshi Morishige (S)

Division of Hematology and Oncology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan.

Shuki Oya (S)

Division of Hematology and Oncology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan.

Yoshitaka Yamasaki (Y)

Division of Hematology and Oncology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan.

Koji Nagafuji (K)

Division of Hematology and Oncology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan.

Naoto Shiba (N)

Department of Orthopedics, Kurume University School of Medicine, Kurume, Japan.

Classifications MeSH