Pleiotropic associations of heterozygosity for the


Journal

ERJ open research
ISSN: 2312-0541
Titre abrégé: ERJ Open Res
Pays: England
ID NLM: 101671641

Informations de publication

Date de publication:
Apr 2021
Historique:
received: 22 01 2021
accepted: 20 02 2021
entrez: 13 5 2021
pubmed: 14 5 2021
medline: 14 5 2021
Statut: epublish

Résumé

Homozygosity for the

Identifiants

pubmed: 33981765
doi: 10.1183/23120541.00049-2021
pii: 00049-2021
pmc: PMC8107350
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Medical Research Council
ID : MC_PC_17228
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_PC_12010
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/P00167X/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : G1000861
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/N011317/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_QA137853
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 202802/Z/16/Z
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 202849/Z/16/Z
Pays : United Kingdom

Informations de copyright

Copyright ©The authors 2021.

Déclaration de conflit d'intérêts

Conflict of interest: K.A. Fawcett reports grants from Asthma UK outside the submitted work. Conflict of interest: K. Song has nothing to disclose. Conflict of interest: G. Qian has nothing to disclose. Conflict of interest: A-E. Farmaki has nothing to disclose. Conflict of interest: R. Packer reports grants from Orion Pharma outside the submitted work. Conflict of interest: C. John reports grants from the Medical Research Council during the conduct of the study. Conflict of interest: N. Shrine has nothing to disclose. Conflict of interest: R. Granell has nothing to disclose. Conflict of interest: S. Ring has nothing to disclose. Conflict of interest: N.J. Timpson has nothing to disclose. Conflict of interest: L.M. Yerges-Armstrong is an employee/stockholder of GlaxoSmithKline. Conflict of interest: R. Eastell reports grants from Amgen and Alexion, grants and personal fees from IDS, Roche and Nittobo, and personal fees from GSK Nutrition, Mereo, Sandoz, AbbVie, Samsung, Haoma Medica, Elsevier, CL Bio, FNIH, Viking, UCSF, Biocon and Lyramid, outside the submitted work. Conflict of interest: L.V. Wain reports grants from GSK outside the submitted work. Conflict of interest: R.A. Scott is an employee and shareholder of GSK. Conflict of interest: M.D. Tobin reports grants from GSK and Orion Pharma outside the submitted work. Conflict of interest: I.P. Hall reports grants from GSK, Boehringer Ingelheim and Orion, outside the submitted work.

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Auteurs

Katherine A Fawcett (KA)

Dept of Health Sciences, University of Leicester, Leicester, UK.

Kijoung Song (K)

Human Genetics, GlaxoSmithKline, Collegeville, PA, USA.

Guoqing Qian (G)

Dept of General Internal Medicine, Ningbo First Hospital, Ningbo City, Zhejiang Province, China.
Division of Respiratory Medicine, University of Nottingham, and NIHR Nottingham BRC, NUH NHS Trust, Nottingham, UK.

Aliki-Eleni Farmaki (AE)

MRC Unit for Lifelong Health and Ageing, Institute of Cardiovascular Science, University College London, London, UK.

Richard Packer (R)

Dept of Health Sciences, University of Leicester, Leicester, UK.

Catherine John (C)

Dept of Health Sciences, University of Leicester, Leicester, UK.

Nick Shrine (N)

Dept of Health Sciences, University of Leicester, Leicester, UK.

Raquel Granell (R)

Medical Research Council Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

Sue Ring (S)

Medical Research Council Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

Nicholas J Timpson (NJ)

Medical Research Council Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

Laura M Yerges-Armstrong (LM)

Human Genetics, GlaxoSmithKline, Collegeville, PA, USA.

Richard Eastell (R)

Dept of Oncology and Metabolism, University of Sheffield, Sheffield, UK.

Louise V Wain (LV)

Dept of Health Sciences, University of Leicester, Leicester, UK.
National Institute for Health Research, Leicester Respiratory Biomedical Research Centre, Glenfield Hospital, Leicester, UK.

Robert A Scott (RA)

Human Genetics - R&D, GSK Medicines Research Centre, Stevenage, UK.

Martin D Tobin (MD)

Dept of Health Sciences, University of Leicester, Leicester, UK.
National Institute for Health Research, Leicester Respiratory Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
These authors contributed equally.

Ian P Hall (IP)

Division of Respiratory Medicine, University of Nottingham, and NIHR Nottingham BRC, NUH NHS Trust, Nottingham, UK.
These authors contributed equally.

Classifications MeSH