Progress in protecting vestibular hair cells.
Hair cells
Ototoxic drugs
Protection
Vestibular dysfunction
Journal
Archives of toxicology
ISSN: 1432-0738
Titre abrégé: Arch Toxicol
Pays: Germany
ID NLM: 0417615
Informations de publication
Date de publication:
08 2021
08 2021
Historique:
received:
17
03
2021
accepted:
29
04
2021
pubmed:
14
5
2021
medline:
12
1
2022
entrez:
13
5
2021
Statut:
ppublish
Résumé
Vestibular hair cells are mechanosensory receptors that are capable of detecting changes in head position and thereby allow animals to maintain their posture and coordinate their movement. Vestibular hair cells are susceptible to ototoxic drugs, aging, and genetic factors that can lead to permanent vestibular dysfunction. Vestibular dysfunction mainly results from the injury of hair cells, which are located in the vestibular sensory epithelium. This review summarizes the mechanisms of different factors causing vestibular hair cell damage and therapeutic strategies to protect vestibular hair cells.
Identifiants
pubmed: 33983457
doi: 10.1007/s00204-021-03067-3
pii: 10.1007/s00204-021-03067-3
pmc: PMC8298329
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
2613-2623Subventions
Organisme : the National Natural Science Foundation of China
ID : Nos. 82071045
Organisme : the National Natural Science Foundation of China
ID : 81870728
Organisme : Shanghai Rising-Star Program
ID : 19QA1401800
Commentaires et corrections
Type : ErratumIn
Informations de copyright
© 2021. The Author(s).
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