Does mRNA SARS-CoV-2 vaccine influence patients' performance during IVF-ET cycle?
COVID-19
IVF
Ovarian stimulation
embryo quality
vaccination
Journal
Reproductive biology and endocrinology : RB&E
ISSN: 1477-7827
Titre abrégé: Reprod Biol Endocrinol
Pays: England
ID NLM: 101153627
Informations de publication
Date de publication:
13 May 2021
13 May 2021
Historique:
received:
22
04
2021
accepted:
06
05
2021
entrez:
14
5
2021
pubmed:
15
5
2021
medline:
20
5
2021
Statut:
epublish
Résumé
No information exists in the literature regarding the effect of mRNA SARS-CoV-2 vaccine on subsequent IVF cycle attempt. We therefore aim to assess the influence of mRNA SARS-CoV-2 vaccine on IVF treatments. An observational study. A tertiary, university-affiliated medical center. All couples undergoing consecutive ovarian stimulation cycles for IVF before and after receiving mRNA SARS-CoV-2 vaccine, and reached the ovum pick-up (OPU) stage. The stimulation characteristics and embryological variables of couples undergoing IVF treatments after receiving mRNA SARS-CoV-2 vaccine were assessed and compared to their IVF cycles prior to vaccination. Stimulation characteristics and embryological variables. Thirty-six couples resumed IVF treatment 7-85 days after receiving mRNA SARS-CoV-2 vaccine. No in-between cycles differences were observed in ovarian stimulation and embryological variables before and after receiving mRNA SARS-CoV-2 vaccination. mRNA SARS-CoV-2 vaccine did not affect patients' performance or ovarian reserve in their immediate subsequent IVF cycle. Future larger studies with longer follow-up will be needed to validate our observations.
Identifiants
pubmed: 33985514
doi: 10.1186/s12958-021-00757-6
pii: 10.1186/s12958-021-00757-6
pmc: PMC8116639
doi:
Substances chimiques
COVID-19 Vaccines
0
RNA, Messenger
0
Types de publication
Journal Article
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
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