Foot ischemia related to essential thrombocytemia and atherosclerosis.
Essential thrombocytemia
Foot ischemia
Myeloproliferative neoplasm
Thrombosis
Journal
Journal de medecine vasculaire
ISSN: 2542-4513
Titre abrégé: J Med Vasc
Pays: France
ID NLM: 101709200
Informations de publication
Date de publication:
May 2021
May 2021
Historique:
received:
19
03
2021
accepted:
19
03
2021
entrez:
15
5
2021
pubmed:
16
5
2021
medline:
29
10
2021
Statut:
ppublish
Résumé
We report two cases of foot ischemia combining microvascular thrombosis related to essential thrombocytemia (ET) and a proximal ulcerating atherosclerotic plaque. This suggests that myeloproliferative neoplasms could also trigger distal embolism from an unstable atherosclerotic plaque by creating a prothrombotic status. These distal ischemic events were the first ET manifestation and therefore lead to myeloproliferative neoplasm diagnosis. In ET, thrombosis event can occur with a normal platelet count. Furthermore, hemogram should be regularly controlled among JAK2 muted patients considering the frequent evolution from isolated JAK2 mutation to ET.
Identifiants
pubmed: 33990286
pii: S2542-4513(21)00055-9
doi: 10.1016/j.jdmv.2021.03.009
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
123-128Informations de copyright
Copyright © 2021. Published by Elsevier Masson SAS.