Frequency of Rh and K antigens in blood donors in Riyadh.
Allele frequency
Antigen frequency
K antigen
Rh antigens
Rh phenotype
Saudi population
Journal
Hematology, transfusion and cell therapy
ISSN: 2531-1387
Titre abrégé: Hematol Transfus Cell Ther
Pays: Brazil
ID NLM: 101725732
Informations de publication
Date de publication:
Historique:
received:
15
11
2020
revised:
17
01
2021
accepted:
17
03
2021
pubmed:
17
5
2021
medline:
17
5
2021
entrez:
16
5
2021
Statut:
ppublish
Résumé
Investigate the prevalence of Rh and the K antigens and their phenotypes in the red blood cells of blood donors in Riyadh, Saudi Arabia. This is a retrospective study. The five principal Rh antigens (D, C, c, E, e) and the Kell antigen from the Kell blood group were tested in 4,675 random samples collected from four blood bank centers in Riyadh. Data were collected for seven weeks (from January 4, 2019 to February 28, 2019). Antigens were tested using the TANGO Optimo system. We found that approximately 86% of the donors had the D antigen, 66% had C, 78% had c, 26% had E, 97% had e and 14% had K. The most common Rh phenotypes were R1r (31%) and R1R1 (22%). The differences in the results between the study population and other populations, such as Caucasian, Indian and African populations indicate the importance of establishing a population-specific database.
Identifiants
pubmed: 33992594
pii: S2531-1379(21)00053-5
doi: 10.1016/j.htct.2021.03.003
pmc: PMC9605887
pii:
doi:
Types de publication
Journal Article
Langues
eng
Pagination
555-559Informations de copyright
Copyright © 2021 Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular. Published by Elsevier España, S.L.U. All rights reserved.
Déclaration de conflit d'intérêts
Conflicts of interest The authors declare that they have no conflicts of interest.
Références
J Blood Med. 2020 Feb 13;11:59-65
pubmed: 32104128
Transfus Apher Sci. 2020 Aug;59(4):102748
pubmed: 32527616
Immunohematology. 2018 Jun;34(2):61-65
pubmed: 29989421
Int J Immunogenet. 2016 Aug;43(4):226-35
pubmed: 27320061
Immunohematology. 2015;31(1):14-9
pubmed: 26308465
Saudi Med J. 2011 Oct;32(10):1039-45
pubmed: 22008924
Lancet Haematol. 2017 May;4(5):e218-e224
pubmed: 28389344
Ann Hum Genet. 1955 Oct;20(2):97-115
pubmed: 13268982
Int J Immunogenet. 2018 Apr;45(2):63-64
pubmed: 29441679
Asian J Transfus Sci. 2013 Jul;7(2):119-24
pubmed: 24014941
Transfus Med. 2012 Oct;22(5):362-6
pubmed: 22757646
Genet Med. 2007 Jun;9(6):372-7
pubmed: 17575503
Blood. 2019 Apr 25;133(17):1814-1820
pubmed: 30808639
Saudi Med J. 1998 May;19(3):265-268
pubmed: 27701539
Vox Sang. 2019 Jan;114(1):95-102
pubmed: 30421425
Blood Transfus. 2014 Jan;12(1):36-9
pubmed: 24120600
J Nat Sci Biol Med. 2017 Jan-Jun;8(1):56-59
pubmed: 28250675
Genet Mol Res. 2015 Jul 14;14(3):7850-63
pubmed: 26214466
Ann Eugen. 1947 Jun;13(4):223
pubmed: 20249864