Nugent Score, Amsel's Criteria, and a Point-of-Care Rapid Test for Diagnosis of Bacterial Vaginosis: Performance in a Cohort of Kenyan Women.
Journal
Sexually transmitted diseases
ISSN: 1537-4521
Titre abrégé: Sex Transm Dis
Pays: United States
ID NLM: 7705941
Informations de publication
Date de publication:
01 01 2022
01 01 2022
Historique:
pubmed:
17
5
2021
medline:
18
3
2022
entrez:
16
5
2021
Statut:
ppublish
Résumé
There are minimal data on the BVBlue test for diagnosis of bacterial vaginosis (BV) in Africa. Among 701 Kenyan women, compared with Nugent score ≥7, the BVBlue test had moderate sensitivity (81.9%; 95% confidence interval, 76.5%-86.5%) and high specificity (92.4%; 95% confidence interval, 89.5%-94.6%). This test may provide a complimentary approach to syndromic management.
Identifiants
pubmed: 33993164
doi: 10.1097/OLQ.0000000000001469
pii: 00007435-202201000-00024
pmc: PMC8590706
mid: NIHMS1724641
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
e22-e25Subventions
Organisme : NICHD NIH HHS
ID : K24 HD088229
Pays : United States
Organisme : NIAID NIH HHS
ID : T32 AI007140
Pays : United States
Organisme : NICHD NIH HHS
ID : F32 HD100202
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR002319
Pays : United States
Organisme : NICHD NIH HHS
ID : R01 HD087346
Pays : United States
Informations de copyright
Copyright © 2021 American Sexually Transmitted Diseases Association. All rights reserved.
Déclaration de conflit d'intérêts
Conflict of Interest and Sources of Funding: R.S.M. receives research funding, paid to the University of Washington, from Hologic Corporation, and has received honoraria for consulting from Lupin Pharmaceuticals. The remaining authors declare no conflict of interest.
Références
Brotman RM. Vaginal microbiome and sexually transmitted infections: An epidemiologic perspective. J Clin Invest 2011; 121:4610–4617.
World Health Organization. Guidelines for the Management of Sexually Transmited Infections. Geneva, Switzerland, 2003.
Verwijs MC, Agaba SK, Sumanyi JC, et al. Targeted point-of-care testing compared with syndromic management of urogenital infections in women (WISH): A cross-sectional screening and diagnostic accuracy study. Lancet Infect Dis 2019; 19:658–669.
Stewart J, Bukusi E, Celum C, et al. Sexually transmitted infections among African women. AIDS 2020; 34:651–658.
Coleman JS, Gaydos CA. Molecular diagnosis of bacterial vaginosis: An update. J Clin Microbiol 2018; 56:e00342–e00318.
Amsel R, Totten PA, Spiegel CA, et al. Nonspecific vaginitis. Diagnostic criteria and microbial and epidemiologic associations. Am J Med 1983; 74:14–22.
Nugent RP, Krohn MA, Hillier SL. Reliability of diagnosing bacterial vaginosis is improved by a standardized method of Gram stain interpretation. J Clin Microbiol 1991; 29:297–301.
Lokken EM, Mandaliya K, Srinivasan S, et al. Impact of preconception vaginal microbiota on women's risk of spontaneous preterm birth: Protocol for a prospective case-cohort study. BMJ Open 2020; 10:e035186.
National AIDS & STI Control Programme of Kenya. Kenya National Guidelines for Prevention, Management and Control of Sexually Transmitted Infections. Nairobi, Kenya, 2018.
Hobbs MM, Steiner MJ, Rich KD, et al. Good performance of rapid prostate-specific antigen test for detection of semen exposure in women: Implications for qualitative research. Sex Transm Dis 2009; 36:501–506.
Bradshaw CS, Morton AN, Garland SM, et al. Evaluation of a point-of-care test, BVBlue, and clinical and laboratory criteria for diagnosis of bacterial vaginosis. J Clin Microbiol 2003; 43:1304–1308.
Kampan NC, Suffian SS, Ithnin NS, et al. Evaluation of BV Blue Test Kit for the diagnosis of bacterial vaginosis. Sex Reprod Healthc 2011; 2:1–5.
Gryphus Diagnostics. Diagnosit BV Blue—Rapid Sialidase Test for Bacterial Vaginosis Package Insert.
Khatoon R, Jahan N, Ahmad S, et al. Comparison of OSOM BV Blue test with conventional methods for diagnosis of bacterial vaginosis. African J Microbiol Res 2013; 7:3698–3703.
Gomaa FA-ZM, Hafex H, Al Anwar A, et al. Diagnosis of bacterial vaginosis among symptomatic Egyptian women: Value of assessing bacterial sialidase activity. Int J Curr Microbiol App Sci 2017; 6:906–917.
Madhivanan P, Krupp K, Li T, et al. Performance of BVBlue rapid test in detecting bacterial vaginosis among women in Mysore, India. Infect Dis Obstet Gynecol 2014; 2014:908313.
Rabe L, Hillier S; on behalf of VOICE Team. Comparison of the BVBlue® Test and the Nugent gram stain score for the diagnosis of bacterial vaginosis (BV). In: Infectious Diseases Society for Obsetrics and Gynecology Annual Scientific Meeting, August 11–13, 2011. Chicago, IL, 2011. p. Abstract.
Hillier S. ClinicalTrials.gov Study Record: A Validation Study of Genzyme Diagnostics OSOM Trichomonas Rapid Test and BVBlue Test [Internet]. ClinicalTrials.gov. Available at: https://clinicaltrials.gov/ct2/show/results/NCT00682851 . Accessed February 18, 2021.
Briselden AM, Moncla BJ, Stevens CE, et al. Sialidases (neuraminidases) in bacterial vaginosis and bacterial vaginosis–associated microflora. J Clin Microbiol 1992; 30:663–666.
Cauci S, Driussi S, Monte R, et al. Immunoglobulin A response against Gardnerella vaginalis hemolysin and sialidase activity in bacterial vaginosis. Am J Obstet Gynecol 1998; 178:511–515.
Peebles K, Kiweewa FM, Palanee-Phillips T, et al; MTN-020/ASPIRE study team. Elevated risk of bacterial vaginosis among users of the copper intrauterine device: A prospective longitudinal cohort study. Clin Infect Dis 2020; ciaa703.
Brooks JP, Edwards DJ, Blithe DL, et al. Effects of combined oral contraceptives, depot medroxyprogesterone acetate and the levonorgestrel-releasing intrauterine system on the vaginal microbiome. Contraception 2017; 95:405–413.