Intramedullary pancreatic adenocarcinoma metastasis: The first case in literature.
Adenocarcinoma de páncreas
Cirugía
Intramedular
Intramedullary
Metastasis
Metástasis
Pancreatic adenocarcinoma
Surgery
Journal
Neurocirugia (English Edition)
ISSN: 2529-8496
Titre abrégé: Neurocirugia (Astur : Engl Ed)
Pays: Spain
ID NLM: 101778588
Informations de publication
Date de publication:
13 May 2021
13 May 2021
Historique:
received:
06
01
2021
revised:
02
03
2021
accepted:
25
03
2021
entrez:
17
5
2021
pubmed:
18
5
2021
medline:
18
5
2021
Statut:
aheadofprint
Résumé
Pancreatic cancer is a common gastrointestinal malignancy, and is often associated with a poor prognosis. Although liver is generally seen as a distant metastasis point, it has been shown that it can metastasize to any organ, especially the gastrointestinal tract, and approximately 0.3% of metastases are observed in spinal cord. We report a 36-year-old woman with a prior history of pancreatic adenocarcinoma who presented to us with a thoracic intramedullary lesion and recent onset of neurological deficits. She underwent surgery with histological confirmation of a diagnosis of metastatic adenocarcinoma. To our knowledge there is no prior report of pure intramedullary spinal cord metastasis from a pancreatic adenocarcinoma in the literature. We report the present patient in view of the rarity of intramedullary spinal cord metastasis and its clinical significance. Although intramedullary metastases are rare, they should be investigated in every patient with malignancy and progressive neurological deficit. While its general prognosis is poor regardless of the type of treatment, early diagnosis and treatment is important in terms of quality of life and survival.
Sections du résumé
BACKGROUND
BACKGROUND
Pancreatic cancer is a common gastrointestinal malignancy, and is often associated with a poor prognosis. Although liver is generally seen as a distant metastasis point, it has been shown that it can metastasize to any organ, especially the gastrointestinal tract, and approximately 0.3% of metastases are observed in spinal cord.
CASE DESCRIPTION
METHODS
We report a 36-year-old woman with a prior history of pancreatic adenocarcinoma who presented to us with a thoracic intramedullary lesion and recent onset of neurological deficits. She underwent surgery with histological confirmation of a diagnosis of metastatic adenocarcinoma.
CONCLUSION
CONCLUSIONS
To our knowledge there is no prior report of pure intramedullary spinal cord metastasis from a pancreatic adenocarcinoma in the literature. We report the present patient in view of the rarity of intramedullary spinal cord metastasis and its clinical significance. Although intramedullary metastases are rare, they should be investigated in every patient with malignancy and progressive neurological deficit. While its general prognosis is poor regardless of the type of treatment, early diagnosis and treatment is important in terms of quality of life and survival.
Identifiants
pubmed: 33994284
pii: S1130-1473(21)00046-4
doi: 10.1016/j.neucir.2021.03.005
pii:
doi:
Types de publication
Case Reports
Langues
eng
spa
Informations de copyright
Copyright © 2021 Sociedad Española de Neurocirugía. Publicado por Elsevier España, S.L.U. All rights reserved.