Outcomes of COVID-19 in Patients with Cirrhosis or Liver Transplantation.
ACE, angiotensin-converting enzyme related carboxypeptidase receptors
ACLF, acute-on chronic liver failure
ALI, acute liver injury
ALT, alanine transaminase
AST, aspartate aminotransferase
CLD, chronic liver disease
COVID-19, Coronavirus disease 2019
HCWs, health care workers
HR, hazard ratio
LFT, liver function tests
LT, liver transplantation
MELD, model for end-stage liver disease
NAFLD, non-alcoholic fatty liver disease
NASH, non-alcoholic steatohepatitis
OR, Odds ratio
SARS-CoV-2
SARS-CoV-2, severe acute respiratory syndrome coronavirus 2
immunosuppression
liver diseases
mortality
nash
Journal
Journal of clinical and experimental hepatology
ISSN: 0973-6883
Titre abrégé: J Clin Exp Hepatol
Pays: India
ID NLM: 101574137
Informations de publication
Date de publication:
Historique:
received:
25
01
2021
accepted:
06
05
2021
pubmed:
18
5
2021
medline:
18
5
2021
entrez:
17
5
2021
Statut:
ppublish
Résumé
Coronavirus disease 2019 (COVID-19) is associated with a significant morbidity and mortality in patients with cirrhosis. There is a significantly higher morbidity and mortality due to COVID-19 in patients with decompensated cirrhosis as compared to compensated cirrhosis, and in patients with cirrhosis as compared to noncirrhotic chronic liver disease. The fear of COVID-19 before or after liver transplantation has lead to a significant reduction in liver transplantation numbers, and patients with decompensated cirrhosis remain at risk of wait list mortality. The studies in liver transplantation recipients show that risk of mortality due to COVID-19 is generally driven by higher age and comorbidities. The current review discusses available literature regarding outcomes of COVID-19 in patients with cirrhosis and outcomes in liver transplant recipients.
Identifiants
pubmed: 33994708
doi: 10.1016/j.jceh.2021.05.003
pii: S0973-6883(21)00105-5
pmc: PMC8112901
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
713-719Informations de copyright
© 2021 Indian National Association for Study of the Liver. Published by Elsevier B.V. All rights reserved.
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