The Clinical Effect of Repetitive Transcranial Magnetic Stimulation on the Disturbance of Consciousness in Patients in a Vegetative State.

brainstem auditory evoked potential electroencephalogram rehabilitation repetitive transcranial magnetic stimulation stroke

Journal

Frontiers in neuroscience
ISSN: 1662-4548
Titre abrégé: Front Neurosci
Pays: Switzerland
ID NLM: 101478481

Informations de publication

Date de publication:
2021
Historique:
received: 05 01 2021
accepted: 19 03 2021
entrez: 17 5 2021
pubmed: 18 5 2021
medline: 18 5 2021
Statut: epublish

Résumé

To explore the effect of combining repetitive transcranial magnetic stimulation (rTMS) and conventional rehabilitation on the recovery of consciousness in patients in a persistent vegetative state (PVS). A total of 48 patients in a PVS were randomly divided into a treatment and control group. Patients in the treatment group were treated with rTMS to stimulate the dorsolateral prefrontal cortex, and patients in the control group were treated with false stimulation. All patients were evaluated using scales and neuroelectrophysiological assessment before treatment, after 30 days of treatment, and following 60 days of treatment. Based on the Coma Recovery Scale-Revised (CRS-R) and electroencephalogram (EEG) grading indexes, the treatment group was significantly higher than those of the control group after 30 and 60 days of treatment. The average difference in the three measurements between the two groups before treatment, at 30 days, and 60 days was 0.04, 1.54, and 2.09 for CRS-R and 0.08, -0.83, and -0.62 for EEG indexes, respectively. The latency periods of each wave of the brainstem auditory evoked potentials (BAEPs) in the treatment group were shorter than those in the control group after 30 and 60 days of treatment. In both groups, the BAEP scores after 30 days of treatment were significantly higher than the scores before treatment, and the scores after 60 days of treatment were higher than the scores after 30 days. In patients in a PVS, rTMS assists in the recovery of consciousness function.

Identifiants

pubmed: 33994925
doi: 10.3389/fnins.2021.647517
pmc: PMC8119637
doi:

Types de publication

Journal Article

Langues

eng

Pagination

647517

Informations de copyright

Copyright © 2021 Zhang, Han, Zeng, Wang and Lv.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Xiao-Hua Zhang (XH)

Department of Rehabilitation, Shenzhen Dapeng New District Nanao People's Hospital, Shenzhen, China.

Ping Han (P)

Department of Rehabilitation, Shenzhen Dapeng New District Nanao People's Hospital, Shenzhen, China.

Yuan-Yuan Zeng (YY)

Department of Rehabilitation, Shenzhen Dapeng New District Nanao People's Hospital, Shenzhen, China.

Yu-Long Wang (YL)

Department of Rehabilitation, The First Affiliated Hospital, Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, China.

Hui-Lan Lv (HL)

Department of Rehabilitation, Shenzhen Dapeng New District Nanao People's Hospital, Shenzhen, China.

Classifications MeSH