Collagen/hyaluronan based hydrogels releasing sulfated hyaluronan improve dermal wound healing in diabetic mice via reducing inflammatory macrophage activity.
4–6): sulfated hyaluronan
Chronic wounds
Hydrogel
Immunomodulation
Macrophages
Skin inflammation
Journal
Bioactive materials
ISSN: 2452-199X
Titre abrégé: Bioact Mater
Pays: China
ID NLM: 101685294
Informations de publication
Date de publication:
Dec 2021
Dec 2021
Historique:
received:
15
12
2020
revised:
14
04
2021
accepted:
15
04
2021
entrez:
17
5
2021
pubmed:
18
5
2021
medline:
18
5
2021
Statut:
epublish
Résumé
Sustained inflammation associated with dysregulated macrophage activation prevents tissue formation and healing of chronic wounds. Control of inflammation and immune cell functions thus represents a promising approach in the development of advanced therapeutic strategies. Here we describe immunomodulatory hyaluronan/collagen (HA-AC/coll)-based hydrogels containing high-sulfated hyaluronan (sHA) as immunoregulatory component for the modulation of inflammatory macrophage activities in disturbed wound healing. Solute sHA downregulates inflammatory activities of bone marrow-derived and tissue-resident macrophages
Identifiants
pubmed: 33997511
doi: 10.1016/j.bioactmat.2021.04.026
pii: S2452-199X(21)00195-X
pmc: PMC8105600
doi:
Types de publication
Journal Article
Langues
eng
Pagination
4342-4359Informations de copyright
© 2021 The Authors.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
Références
Am J Pathol. 1998 Jun;152(6):1445-52
pubmed: 9626049
Wound Repair Regen. 2009 Nov-Dec;17(6):763-71
pubmed: 19903300
Front Physiol. 2018 May 01;9:419
pubmed: 29765329
J Exp Med. 2015 Apr 6;212(4):447-56
pubmed: 25800956
J Invest Dermatol. 2017 Apr;137(4):941-950
pubmed: 28017830
Diabetes. 2014 Mar;63(3):1103-14
pubmed: 24194505
Biomatter. 2012 Oct-Dec;2(4):226-36
pubmed: 23507888
Arch Dermatol Res. 2007 Feb;298(9):413-20
pubmed: 17091276
Wound Repair Regen. 2006 May-Jun;14(3):252-8
pubmed: 16808803
J Cell Biochem. 2014 Sep;115(9):1561-71
pubmed: 24706396
Acta Biomater. 2013 Mar;9(3):5621-9
pubmed: 23168224
Sci Transl Med. 2014 Dec 3;6(265):265sr6
pubmed: 25473038
Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Jul;1864(7):1017-1030
pubmed: 30953761
Acta Biomater. 2017 Apr 15;53:13-28
pubmed: 28119112
Wound Repair Regen. 2014 Sep-Oct;22(5):579-93
pubmed: 25039417
J Clin Invest. 1996 Nov 15;98(10):2403-13
pubmed: 8941660
Drug Metab Pharmacokinet. 2009;24(4):300-7
pubmed: 19745557
J Wound Care. 2016 May;25(5):277-87
pubmed: 27169343
J Biomed Mater Res B Appl Biomater. 2012 Feb;100(2):331-41
pubmed: 22102613
J Pathol. 2015 Aug;236(4):433-44
pubmed: 25875529
J Cell Sci. 2012 Jul 1;125(Pt 13):3015-24
pubmed: 22797912
J Clin Invest. 2011 Mar;121(3):985-97
pubmed: 21317534
Bioeng Transl Med. 2017 May 16;2(2):139-155
pubmed: 28932817
Neuro Endocrinol Lett. 2009;30 Suppl 1:106-11
pubmed: 20027154
Nat Med. 2005 Nov;11(11):1173-9
pubmed: 16244651
ILAR J. 2015;56(1):127-38
pubmed: 25991704
F1000Prime Rep. 2014 Mar 03;6:13
pubmed: 24669294
Cell Rep. 2016 Mar 22;14(11):2611-23
pubmed: 26971994
Eur J Immunol. 2018 Sep;48(9):1445-1455
pubmed: 29879295
ACS Appl Mater Interfaces. 2015 Oct 28;7(42):23787-97
pubmed: 26452150
Adv Wound Care (New Rochelle). 2015 Aug 1;4(8):490-500
pubmed: 26244105
Wound Repair Regen. 2014 Sep-Oct;22(5):569-78
pubmed: 24942811
Carbohydr Polym. 2020 Aug 1;241:116364
pubmed: 32507198
Trends Immunol. 2005 Dec;26(12):637-43
pubmed: 16214414
Diabetes. 2013 Jul;62(7):2579-87
pubmed: 23493576
Cell Res. 2020 Apr;30(4):315-327
pubmed: 32152420
Int Immunol. 2018 Oct 29;30(11):485-491
pubmed: 30371831
ACS Biomater Sci Eng. 2015 Jul 13;1(7):481-493
pubmed: 26280020
J Dev Biol. 2016 Jun 22;4(2):
pubmed: 29615587
J Immunol. 2010 Apr 1;184(7):3964-77
pubmed: 20176743
Am J Pathol. 2013 Nov;183(5):1352-1363
pubmed: 24091222
J Invest Dermatol. 2014 Feb;134(2):526-537
pubmed: 23921952
Int J Mol Med. 2015 Apr;35(4):1017-25
pubmed: 25647660
Sci Rep. 2019 Dec 2;9(1):18143
pubmed: 31792253
Blood. 2011 Jul 14;118(2):330-8
pubmed: 21551236
Acta Biomater. 2019 Mar 1;86:135-147
pubmed: 30660005
Science. 2002 Apr 5;296(5565):155-8
pubmed: 11935029
Anal Biochem. 1965 Sep;12(3):559-64
pubmed: 5859517
Biochem Pharmacol. 2014 Nov 1;92(1):131-41
pubmed: 25175736
Stem Cells. 2007 Oct;25(10):2648-59
pubmed: 17615264
Med Eng Phys. 2008 Jun;30(5):599-606
pubmed: 17869160
J Histochem Cytochem. 2008 Jul;56(7):687-96
pubmed: 18413645
Eur J Immunol. 2016 Aug;46(8):2043-53
pubmed: 27214608
Glycoconj J. 2010 Jan;27(1):151-8
pubmed: 19941065
Carbohydr Polym. 2013 Apr 2;93(2):438-41
pubmed: 23499080
Immunity. 2015 Oct 20;43(4):803-16
pubmed: 26474656
Biomaterials. 2016 Jan;77:130-138
pubmed: 26588795
J Clin Invest. 2019 Jul 22;129(8):2983-2993
pubmed: 31329162
J Invest Dermatol. 2007 Sep;127(9):2259-67
pubmed: 17460730
Biochem Pharmacol. 2018 Jul;153:159-167
pubmed: 29452096
Tissue Eng. 2007 Jun;13(6):1299-312
pubmed: 17518741
J Invest Dermatol. 2018 Sep;138(9):1999-2009
pubmed: 29605673
Acta Biomater. 2017 Feb;49:1-15
pubmed: 27915024
Arch Biochem Biophys. 2014 Dec 15;564:83-8
pubmed: 25241054
J Mater Sci Mater Med. 2019 May 24;30(6):65
pubmed: 31127393
Biomacromolecules. 2009 Dec 14;10(12):3290-7
pubmed: 19894734
J Invest Dermatol. 2015 Jun;135(6):1700-1703
pubmed: 25647438
Sci Transl Med. 2017 Apr 19;9(386):
pubmed: 28424334
Biomacromolecules. 2016 Nov 14;17(11):3694-3705
pubmed: 27775884
ACS Appl Mater Interfaces. 2017 Mar 22;9(11):9539-9550
pubmed: 28248081
Biomaterials. 2011 Oct;32(28):6692-709
pubmed: 21715002
Biochim Biophys Acta. 1986 Sep 4;883(2):173-7
pubmed: 3091074
Proteomics. 2017 May;17(10):e1700082
pubmed: 28337837
Biomed Res Int. 2014;2014:986594
pubmed: 24971366
Science. 2009 Nov 27;326(5957):1216-9
pubmed: 19965464
Adv Ther. 2017 Mar;34(3):599-610
pubmed: 28108895
Cytokine. 2011 Nov;56(2):256-64
pubmed: 21803601
J Immunol. 2009 Jul 15;183(2):787-91
pubmed: 19570822
Nat Med. 2009 Jan;15(1):42-9
pubmed: 19098906
Immunol Res. 2005;31(3):207-18
pubmed: 15888912
J Cell Sci. 2003 Aug 1;116(Pt 15):3227-38
pubmed: 12829742
PLoS One. 2011 Feb 09;6(2):e16658
pubmed: 21347371
Proc Natl Acad Sci U S A. 1976 Jan;73(1):183-7
pubmed: 1061114
Front Pharmacol. 2020 Jan 29;10:1661
pubmed: 32082161
Macromol Biosci. 2017 Nov;17(11):
pubmed: 28683182
Ann Rheum Dis. 2004 Nov;63 Suppl 2:ii84-ii89
pubmed: 15479880
Semin Cell Dev Biol. 2009 Jul;20(5):517-27
pubmed: 19393325
Stem Cell Res Ther. 2020 Jun 11;11(1):232
pubmed: 32527289
Int J Mol Sci. 2019 Jul 06;20(13):
pubmed: 31284572
Immunity. 2016 Mar 15;44(3):450-462
pubmed: 26982353
Biomolecules. 2020 Dec 29;11(1):
pubmed: 33383795
Adv Wound Care (New Rochelle). 2014 Oct 1;3(10):647-661
pubmed: 25302139
J Biol Chem. 1951 Nov;193(1):265-75
pubmed: 14907713
Tissue Eng Part A. 2017 Oct;23(19-20):1152-1159
pubmed: 28457179
J Immunol. 2009 May 1;182(9):5836-45
pubmed: 19380832