Financial Conflicts of Interest in Clinical Practice Guidelines: A Systematic Review.

CMS-OP, Centers for Medicare & Medicaid Services Open Payments CPG, clinical practice guideline FCOI, financial conflicts of interest

Journal

Mayo Clinic proceedings. Innovations, quality & outcomes
ISSN: 2542-4548
Titre abrégé: Mayo Clin Proc Innov Qual Outcomes
Pays: Netherlands
ID NLM: 101728275

Informations de publication

Date de publication:
Apr 2021
Historique:
entrez: 17 5 2021
pubmed: 18 5 2021
medline: 18 5 2021
Statut: epublish

Résumé

To systematically evaluate the prevalence of disclosed and undisclosed financial conflicts of interest (FCOI) among clinical practice guidelines (CPGs). In this systematic review, we ascertained the prevalence and types of FCOI for CPGs from January 1, 1980, to March 3, 2019. The primary outcome was the prevalence of FCOI among authors of CPGs. FCOI disclosures were compared between medical subspecialties and societies producing CPGs. Among the 37 studies including 14,764 total guideline authors, 45% had at least one FCOI. The prevalence of FCOI per study ranged from 6% to 100%. More authors had FCOI involving general payments (39%) compared with research payments (29%). Oncology, neurology, and gastroenterology had the highest prevalence of FCOI compared with other medical specialties. Among the 8 studies that included the monetary values in US dollars of FCOI, average payments per author ranged from $578 to $242,300. Among the 10 studies that included data on undisclosed FCOI, 32% of authors had undisclosed industry payments. There are numerous FCOI among authors of CPGs, many of which are undisclosed

Identifiants

pubmed: 33997642
doi: 10.1016/j.mayocpiqo.2020.09.016
pii: S2542-4548(20)30200-9
pmc: PMC8105509
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

466-475

Informations de copyright

© 2020 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc.

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Auteurs

Sahar Tabatabavakili (S)

Department of Medicine, University of Toronto, Ontario, Canada.
Division of Gastroenterology, St. Michael's Hospital, Toronto, Ontario, Canada.

Rishad Khan (R)

Department of Medicine, University of Toronto, Ontario, Canada.

Michael A Scaffidi (MA)

Division of Gastroenterology, St. Michael's Hospital, Toronto, Ontario, Canada.
Faculty of Health Sciences, School of Medicine, Queen's University, Kingston, Ontario, Canada.

Nikko Gimpaya (N)

Division of Gastroenterology, St. Michael's Hospital, Toronto, Ontario, Canada.

David Lightfoot (D)

Health Science Library, Unity Health Toronto, St. Michael's Hospital, Toronto, Ontario, Canada.

Samir C Grover (SC)

Department of Medicine, University of Toronto, Ontario, Canada.
Division of Gastroenterology, St. Michael's Hospital, Toronto, Ontario, Canada.
Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada.

Classifications MeSH