MyoD induces ARTD1 and nucleoplasmic poly-ADP-ribosylation during fibroblast to myoblast transdifferentiation.

Biological Sciences Cell Biology Developmental Biology Molecular Biology

Journal

iScience
ISSN: 2589-0042
Titre abrégé: iScience
Pays: United States
ID NLM: 101724038

Informations de publication

Date de publication:
21 May 2021
Historique:
received: 30 06 2020
revised: 27 03 2021
accepted: 11 04 2021
entrez: 17 5 2021
pubmed: 18 5 2021
medline: 18 5 2021
Statut: epublish

Résumé

While protein ADP-ribosylation was reported to regulate differentiation and dedifferentiation, it has so far not been studied during transdifferentiation. Here, we found that MyoD-induced transdifferentiation of fibroblasts to myoblasts promotes the expression of the ADP-ribosyltransferase

Identifiants

pubmed: 33997706
doi: 10.1016/j.isci.2021.102432
pii: S2589-0042(21)00400-4
pmc: PMC8102911
doi:

Types de publication

Journal Article

Langues

eng

Pagination

102432

Subventions

Organisme : NIGMS NIH HHS
ID : R01 GM134712
Pays : United States

Informations de copyright

© 2021 The Author(s).

Déclaration de conflit d'intérêts

The authors declare no financial interest.

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Auteurs

Lavinia Bisceglie (L)

Department of Molecular Mechanisms of Disease, University of Zurich, Zurich, Switzerland.
Molecular Life Science PhD Program of the Life Science Zurich Graduate School, University of Zurich, Zurich, Switzerland.

Ann-Katrin Hopp (AK)

Department of Molecular Mechanisms of Disease, University of Zurich, Zurich, Switzerland.

Kapila Gunasekera (K)

Department of Molecular Mechanisms of Disease, University of Zurich, Zurich, Switzerland.

Roni H Wright (RH)

Centre de Regulació Genomica (CRG), Barcelona Institute of Science and Technology (BIST), Dr. Aiguader 88, 08003 Barcelona, Spain.
Basic Sciences Department, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya (UIC), 08003 Barcelona, Spain.

François Le Dily (F)

Centre de Regulació Genomica (CRG), Barcelona Institute of Science and Technology (BIST), Dr. Aiguader 88, 08003 Barcelona, Spain.

Enrique Vidal (E)

Centre de Regulació Genomica (CRG), Barcelona Institute of Science and Technology (BIST), Dr. Aiguader 88, 08003 Barcelona, Spain.

Alessandra Dall'Agnese (A)

Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.

Luca Caputo (L)

Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.

Chiara Nicoletti (C)

Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.

Pier Lorenzo Puri (PL)

Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.

Miguel Beato (M)

Centre de Regulació Genomica (CRG), Barcelona Institute of Science and Technology (BIST), Dr. Aiguader 88, 08003 Barcelona, Spain.
Universitat Pompeu Fabra (UPF), Barcelona, Spain.

Michael O Hottiger (MO)

Department of Molecular Mechanisms of Disease, University of Zurich, Zurich, Switzerland.

Classifications MeSH