Association of adipocytokine IL-1A and IL-6 genes with intramuscular fat content and fatty acid composition in pigs.

Adipose Tissue Animals Fatty Acids / analysis Female Interleukin-1alpha / genetics Interleukin-6 / genetics Male Muscle, Skeletal / metabolism Polymorphism, Single Nucleotide Pork Meat / analysis Sus scrofa / genetics
Fatty acid IL-1A IL-6 Intramuscular fat Pigs

Journal

Meat science
ISSN: 1873-4138
Titre abrégé: Meat Sci
Pays: England
ID NLM: 101160862

Informations de publication

Date de publication:
Sep 2021
Historique:
received: 20 10 2020
revised: 22 03 2021
accepted: 07 05 2021
pubmed: 18 5 2021
medline: 29 9 2021
entrez: 17 5 2021
Statut: ppublish

Résumé

Several adipocytokines are involved in inflammatory and immune responses as well as regulated fat deposition and lipid metabolism in mammals. This study aimed to verify the polymorphisms of the porcine interleukin 1A (IL-1A) and interleukin 6 (IL-6) genes and to assess their association with intramuscular fat (IMF) content and fatty acid (FA) composition in commercial crossbred pigs. Two single nucleotide polymorphisms (SNPs) of the porcine IL-1A g.43722547A>G and IL-6 g.91508173C>T loci were found to be segregating in these crossbred pigs. Furthermore, the porcine IL-1A g.43722547A>G polymorphism was found to be significantly associated with myristic, palmitic, palmitoleic, and eicosadienoic acid levels. Moreover, the porcine IL-6 g.91508173C>T polymorphism was significantly associated with IMF content and homolinolenic acid levels. These results suggest that the polymorphisms of the porcine IL-1A and IL-6 genes correlated with lipid content and FA composition and confirmed the importance of the adipocytokine IL-1A and IL-6 genes as candidate genes for fatty acid composition in the muscles of pigs.

Identifiants

DOI: 10.1016/j.meatsci.2021.108554 PMID: 34000609
pubmed: 34000609
pii: S0309-1740(21)00130-3
doi: 10.1016/j.meatsci.2021.108554
pii:
doi:

Substances chimiques

Fatty Acids 0
Interleukin-1alpha 0
Interleukin-6 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

108554

Informations de copyright

Copyright © 2021 Elsevier Ltd. All rights reserved.

Auteurs

Nanthana Pothakam (N)

Department of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand; Center of Excellence on Agricultural Biotechnology: (AG-BIO/PERDO-CHE), Bangkok 10900, Thailand; Graduate School, Chiang Mai University, Chiang Mai 50200, Thailand.

Pantaporn Supakankul (P)

Division of Animal Science, School of Agriculture and Natural Resources, University of Phayao, Phayao 56000, Thailand.

Worrarak Norseeda (W)

Department of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand; Center of Excellence on Agricultural Biotechnology: (AG-BIO/PERDO-CHE), Bangkok 10900, Thailand; Graduate School, Chiang Mai University, Chiang Mai 50200, Thailand.

Guisheng Liu (G)

Institute of Animal Science and Veterinary Medicine, Hubei Academy of Agricultural Sciences, Wuhan 430064, China; Hubei Key Lab for Animal Embryo Engineering and Molecular Breeding, Wuhan 430064, China.

Tawatchai Teltathum (T)

Mae Hong Son Livestock Research and Breeding Center, Mae Hong Son 58000, Thailand.

Watcharapong Naraballobh (W)

Department of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand.

Trisadee Khamlor (T)

Department of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand.

Korawan Sringarm (K)

Department of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand; Center of Excellence on Agricultural Biotechnology: (AG-BIO/PERDO-CHE), Bangkok 10900, Thailand; Cluster of Research and Development of Pharmaceutical and Natural Products Innovation for Human or Animal, Chiang Mai University, Chiang Mai 50200, Thailand.

Supamit Mekchay (S)

Department of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand; Center of Excellence on Agricultural Biotechnology: (AG-BIO/PERDO-CHE), Bangkok 10900, Thailand; Cluster of Research and Development of Pharmaceutical and Natural Products Innovation for Human or Animal, Chiang Mai University, Chiang Mai 50200, Thailand; Innovative Agriculture Research Center, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand. Electronic address: supamitmekchay@gmail.com.

Articles similaires

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Meal Timing and Anthropometric and Metabolic Outcomes: A Systematic Review and Meta-Analysis.

Hiu Yee Liu, Ashley A Eso, Nathan Cook et al.
1.00
Humans Meals Time Factors Female Adult

Classifications MeSH

questionsmedicales.fr › Tissus › Tissu conjonctif › Tissu adipeux › Association of adipocytokine IL-1A and IL-6...
questionsmedicales.fr › Eucaryotes › Animaux › Association of adipocytokine IL-1A and IL-6...
questionsmedicales.fr › Lipides › Acides gras › Association of adipocytokine IL-1A and IL-6...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Monokines › Interleukine-1 › Interleukine-1 alpha › Association of adipocytokine IL-1A and IL-6...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Interleukines › Interleukine-6 › Association of adipocytokine IL-1A and IL-6...
questionsmedicales.fr › Tissus › Muscles › Muscle strié › Muscles squelettiques › Association of adipocytokine IL-1A and IL-6...
questionsmedicales.fr › Phénomènes génétiques › Variation génétique › Polymorphisme génétique › Polymorphisme de nucléotide simple › Association of adipocytokine IL-1A and IL-6...
questionsmedicales.fr › Aliments et boissons › Aliments › Viande › Viande rouge › Viande de porc › Association of adipocytokine IL-1A and IL-6...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Artiodactyla › Suidae › Sus scrofa › Association of adipocytokine IL-1A and IL-6...