Evaluation of Spin in the Abstracts of Systematic Reviews and Meta-Analyses of Atopic Dermatitis Treatments and Interventions.

Atopic dermatitis Eczema Spin Treatment

Journal

Dermatology (Basel, Switzerland)
ISSN: 1421-9832
Titre abrégé: Dermatology
Pays: Switzerland
ID NLM: 9203244

Informations de publication

Date de publication:
17 May 2021
Historique:
received: 21 10 2020
accepted: 25 12 2020
entrez: 17 5 2021
pubmed: 18 5 2021
medline: 18 5 2021
Statut: aheadofprint

Résumé

Spin - the misrepresentation of a study's results - has been identified in abstracts of studies focused on a variety of disorders from multiple fields of medicine. This study's primary objective was to evaluate the abstracts of systematic reviews and meta-analyses focused on the treatment of atopic dermatitis for the nine most severe forms of spin. We systematically searched Embase and MEDLINE for systematic reviews of atopic dermatitis therapies. Screening and data extraction occurred in a masked, duplicate fashion. Each included study was evaluated for the nine most severe types of spin and other study characteristics. Our searches retrieved 2,456 studies, of which 113 were included for data extraction. Spin was found in 74.3% of our included studies (84/113). Spin type 6 occurred most frequently (68/113, 60.2%). Spin types 1, 2, and 9 were not identified. All industry-funded systematic reviews contained spin in their abstract. The presence of spin was not associated with any specific study characteristics, including the methodological quality of the study. Severe forms of spin were found in the majority of abstracts for systematic reviews of atopic dermatitis treatments. Steps should be taken to prevent spin to improve the quality of reporting in abstracts.

Sections du résumé

BACKGROUND BACKGROUND
Spin - the misrepresentation of a study's results - has been identified in abstracts of studies focused on a variety of disorders from multiple fields of medicine.
OBJECTIVES OBJECTIVE
This study's primary objective was to evaluate the abstracts of systematic reviews and meta-analyses focused on the treatment of atopic dermatitis for the nine most severe forms of spin.
METHODS METHODS
We systematically searched Embase and MEDLINE for systematic reviews of atopic dermatitis therapies. Screening and data extraction occurred in a masked, duplicate fashion. Each included study was evaluated for the nine most severe types of spin and other study characteristics.
RESULTS RESULTS
Our searches retrieved 2,456 studies, of which 113 were included for data extraction. Spin was found in 74.3% of our included studies (84/113). Spin type 6 occurred most frequently (68/113, 60.2%). Spin types 1, 2, and 9 were not identified. All industry-funded systematic reviews contained spin in their abstract. The presence of spin was not associated with any specific study characteristics, including the methodological quality of the study.
CONCLUSIONS CONCLUSIONS
Severe forms of spin were found in the majority of abstracts for systematic reviews of atopic dermatitis treatments. Steps should be taken to prevent spin to improve the quality of reporting in abstracts.

Identifiants

pubmed: 34000718
pii: 000515299
doi: 10.1159/000515299
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

496-505

Informations de copyright

© 2021 S. Karger AG, Basel.

Auteurs

Vanessa Lin (V)

Office of Medical Student Research, Oklahoma State University Center for Health Sciences, Tulsa, Oklahoma, USA.

Raahi Patel (R)

Office of Medical Student Research, Oklahoma State University Center for Health Sciences, Tulsa, Oklahoma, USA.
Arkansas Colleges of Health Education, Fort Smith, Arkansas, USA.

Alexis Wirtz (A)

Office of Medical Student Research, Oklahoma State University Center for Health Sciences, Tulsa, Oklahoma, USA.
Arkansas Colleges of Health Education, Fort Smith, Arkansas, USA.

Deepika Mannem (D)

Office of Medical Student Research, Oklahoma State University Center for Health Sciences, Tulsa, Oklahoma, USA.
Arkansas Colleges of Health Education, Fort Smith, Arkansas, USA.

Ryan Ottwell (R)

Office of Medical Student Research, Oklahoma State University Center for Health Sciences, Tulsa, Oklahoma, USA.

Wade Arthur (W)

Office of Medical Student Research, Oklahoma State University Center for Health Sciences, Tulsa, Oklahoma, USA.

Courtney Cook (C)

Department of Dermatology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.

Hannah Howard (H)

Utica Park Clinic Dermatology, Tulsa, Oklahoma, USA.

Drew Wright (D)

Samuel J. Wood Library & C.V. Starr Biomedical Information Center, Weill Cornell Medical College, New York, New York, New York, USA.

Micah Hartwell (M)

Office of Medical Student Research, Oklahoma State University Center for Health Sciences, Tulsa, Oklahoma, USA.
Department of Psychiatry and Behavioral Sciences, Oklahoma State University Center for Health Sciences, Tulsa, Oklahoma, USA.

Matt Vassar (M)

Department of Psychiatry and Behavioral Sciences, Oklahoma State University Center for Health Sciences, Tulsa, Oklahoma, USA.

Classifications MeSH