Prevalence of autism spectrum disorder and autistic traits in children with anorexia nervosa and avoidant/restrictive food intake disorder.

Anorexia Autism Comorbidity Feed and eating disorders

Journal

BioPsychoSocial medicine
ISSN: 1751-0759
Titre abrégé: Biopsychosoc Med
Pays: England
ID NLM: 101286572

Informations de publication

Date de publication:
17 May 2021
Historique:
received: 15 12 2020
accepted: 04 05 2021
entrez: 18 5 2021
pubmed: 19 5 2021
medline: 19 5 2021
Statut: epublish

Résumé

Autism spectrum disorder (ASD) and feeding and eating disorders (FEDs) such as anorexia nervosa (AN) are strongly linked as evidenced by frequent comorbidity and overlapping traits. However, eating and social behaviors are shaped by culture, so it is critical to examine these associations in different populations. Moreover, FEDs are heterogeneous, and there has been no examination of autistic traits in avoidant/restrictive food intake disorder (ARFID). Therefore, we investigated the prevalence of ASD and autistic traits among Japanese children with AN (n = 92) or ARFID (n = 32) from a prospective multicenter cohort study using the Autism Spectrum Quotient Children's version (AQC) and Children's Eating Attitudes Test (ChEAT26). ASD prevalence was high in both AN and ARFID (16.3 and 12.5%, respectively). The AN group exhibited significantly higher scores on all AQC subscales than an age-matched healthy control (HC) group, but there were no significant correlations between AQC scores and ChEAT26 scores. In the AFRID group, AQC scores did not differ from HCs, but significant correlations were found between total AQC and ChEAT26 scores and between several AQC and ChEAT26 subscales. Both the AN and ARFID groups had high prevalence rates of ASD. The AN group showed a significantly higher degree of autistic traits than the HC group; however, no difference was found between the ARFID and HC groups. Clinicians need to be aware of these rates when working with children with ED.

Sections du résumé

BACKGROUND BACKGROUND
Autism spectrum disorder (ASD) and feeding and eating disorders (FEDs) such as anorexia nervosa (AN) are strongly linked as evidenced by frequent comorbidity and overlapping traits. However, eating and social behaviors are shaped by culture, so it is critical to examine these associations in different populations. Moreover, FEDs are heterogeneous, and there has been no examination of autistic traits in avoidant/restrictive food intake disorder (ARFID).
METHODS METHODS
Therefore, we investigated the prevalence of ASD and autistic traits among Japanese children with AN (n = 92) or ARFID (n = 32) from a prospective multicenter cohort study using the Autism Spectrum Quotient Children's version (AQC) and Children's Eating Attitudes Test (ChEAT26).
RESULTS RESULTS
ASD prevalence was high in both AN and ARFID (16.3 and 12.5%, respectively). The AN group exhibited significantly higher scores on all AQC subscales than an age-matched healthy control (HC) group, but there were no significant correlations between AQC scores and ChEAT26 scores. In the AFRID group, AQC scores did not differ from HCs, but significant correlations were found between total AQC and ChEAT26 scores and between several AQC and ChEAT26 subscales.
CONCLUSIONS CONCLUSIONS
Both the AN and ARFID groups had high prevalence rates of ASD. The AN group showed a significantly higher degree of autistic traits than the HC group; however, no difference was found between the ARFID and HC groups. Clinicians need to be aware of these rates when working with children with ED.

Identifiants

DOI: 10.1186/s13030-021-00212-3 PMID: 34001197 PMC: PMC8130445
pubmed: 34001197
doi: 10.1186/s13030-021-00212-3
pii: 10.1186/s13030-021-00212-3
pmc: PMC8130445
doi:

Types de publication

Journal Article

Langues

eng

Pagination

9

Subventions

Organisme : Ministry of Health, Labour and Welfare
ID : 29040501

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Auteurs

Takeshi Inoue (T)

Dokkyo Medical University Saitama Medical Center, Child Development and Psychosomatic Medicine Center, 2-1-50, Minami-Koshigaya, Koshigaya-shi, Saitama-Ken, 343-8555, Japan. tinoue0123@gmail.com.
Department of Pediatrics, Dokkyo Medical University Saitama Medical Center, Saitama, Japan. tinoue0123@gmail.com.
ORCID: 0000-0002-7262-0482

Ryoko Otani (R)

Dokkyo Medical University Saitama Medical Center, Child Development and Psychosomatic Medicine Center, 2-1-50, Minami-Koshigaya, Koshigaya-shi, Saitama-Ken, 343-8555, Japan.

Toshiyuki Iguchi (T)

Department of Pediatrics, Hoshigaoka Maternity Hospital, Aichi, Japan.

Ryuta Ishii (R)

Department of Pediatrics and Child health, Kurume University School of Medicine, Fukuoka, Japan.

Soh Uchida (S)

Department of Pediatrics, Tachikawa Hospital, Tokyo, Japan.

Ayumi Okada (A)

Department of Pediatrics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.

Shinji Kitayama (S)

Himeji City Center for the Disabled, Hyogo, Japan.

Kenshi Koyanagi (K)

Nagasaki Prefectural Center of Medicine and Welfare for Children, Nagasaki, Japan.

Yuki Suzuki (Y)

Department of Pediatrics, National Hospital Organization Mie National Hospital, Mie, Japan.

Yuichi Suzuki (Y)

Department of Pediatrics, Fukushima Medical University School of Medicine, Fukushima, Japan.

Yoshino Sumi (Y)

Mental and developmental clinic for children "Elm Tree", Hokaido, Japan.

Shizuo Takamiya (S)

Psychiatry Department, Kobe City Nishi-Kobe Medical Center, Hyogo, Japan.
Takamiya Psychiatry Clinic, Hyogo, Japan.

Yasuko Tsurumaru (Y)

Department of Pediatrics, Okayama University Hospital, Okayama, Japan.

Shinichiro Nagamitsu (S)

Department of Pediatrics and Child health, Kurume University School of Medicine, Fukuoka, Japan.

Yoshimitsu Fukai (Y)

Tokyo Metropolitan Children's Medical Center, Psychosomatic Medicine, Tokyo, Japan.

Chikako Fujii (C)

Department of Pediatrics, Okayama University Hospital, Okayama, Japan.

Michiko Matsuoka (M)

Department of Neuropsychiatry, Kurume University School of Medicine, Fukuoka, Japan.

Junpei Iwanami (J)

Dokkyo Medical University Saitama Medical Center, Child Development and Psychosomatic Medicine Center, 2-1-50, Minami-Koshigaya, Koshigaya-shi, Saitama-Ken, 343-8555, Japan.

Akio Wakabayashi (A)

Department of Psychology, Chiba University, Chiba, Japan.

Ryoichi Sakuta (R)

Dokkyo Medical University Saitama Medical Center, Child Development and Psychosomatic Medicine Center, 2-1-50, Minami-Koshigaya, Koshigaya-shi, Saitama-Ken, 343-8555, Japan.

Classifications MeSH