Genetic variants associated with serum alanine aminotransferase levels among patients with hepatitis C virus infection: A genome-wide association study.
ALT serial test
Taiwan biobank
hepatocellular carcinoma
quantitative trait
Journal
Journal of viral hepatitis
ISSN: 1365-2893
Titre abrégé: J Viral Hepat
Pays: England
ID NLM: 9435672
Informations de publication
Date de publication:
09 2021
09 2021
Historique:
revised:
12
03
2021
received:
08
02
2021
accepted:
17
04
2021
pubmed:
19
5
2021
medline:
5
10
2021
entrez:
18
5
2021
Statut:
ppublish
Résumé
Information on genetic variants associated with elevated serum alanine aminotransferase (ALT) levels remains limited. A genome-wide association study was performed to identify single-nucleotide polymorphisms (SNPs) associated with ALT levels. The ALT-associated SNP was further evaluated for hepatocellular carcinoma (HCC) risk. A cohort of 892 anti-HCV seropositive patients was used for genome-wide SNP array to examine the associations with baseline ALT levels. SNPs <10
Substances chimiques
Alanine Transaminase
EC 2.6.1.2
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1265-1273Subventions
Organisme : Ministry of Science and Technology, Taipei, Taiwan
Informations de copyright
© 2021 John Wiley & Sons Ltd.
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