Cyclic Ion Mobility-Collision Activation Experiments Elucidate Protein Behavior in the Gas Phase.


Journal

Journal of the American Society for Mass Spectrometry
ISSN: 1879-1123
Titre abrégé: J Am Soc Mass Spectrom
Pays: United States
ID NLM: 9010412

Informations de publication

Date de publication:
02 Jun 2021
Historique:
pubmed: 20 5 2021
medline: 15 12 2021
entrez: 19 5 2021
Statut: ppublish

Résumé

Ion mobility coupled to mass spectrometry (IM-MS) is widely used to study protein dynamics and structure in the gas phase. Increasing the energy with which the protein ions are introduced to the IM cell can induce them to unfold, providing information on the comparative energetics of unfolding between different proteoforms. Recently, a high-resolution cyclic IM-mass spectrometer (cIM-MS) was introduced, allowing multiple, consecutive tandem IM experiments (IM

Identifiants

pubmed: 34006100
doi: 10.1021/jasms.1c00018
pmc: PMC8172447
mid: NIHMS1705723
doi:

Substances chimiques

Gases 0
Ions 0
Cytochromes c 9007-43-6
BIRC3 protein, human EC 2.3.2.27
Baculoviral IAP Repeat-Containing 3 Protein EC 2.3.2.27

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1545-1552

Subventions

Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 209250/Z/17/Z
Pays : United Kingdom
Organisme : NIGMS NIH HHS
ID : R01 GM078114
Pays : United States

Références

Protein Sci. 2008 Sep;17(9):1467-74
pubmed: 18556473
Anal Chem. 2014 Nov 18;86(22):10979-91
pubmed: 25353392
J Biomol Tech. 2002 Sep;13(3):101-18
pubmed: 19498975
Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19285-90
pubmed: 24218609
Chem Sci. 2017 Jul 1;8(7):5030-5040
pubmed: 28970890
Anal Chem. 2005 Oct 1;77(19):6381-8
pubmed: 16194103
J Mol Biol. 2002 Oct 4;322(5):1013-24
pubmed: 12367525
Int J Mass Spectrom. 2013 Jul 1;345-347:54-62
pubmed: 25844045
Chem Biol. 2013 Nov 21;20(11):1411-20
pubmed: 24210218
Proc Natl Acad Sci U S A. 1987 Dec;84(23):8628-32
pubmed: 3317417
Anal Chem. 2017 Jul 18;89(14):7527-7534
pubmed: 28636328
Physiol Rev. 2011 Jul;91(3):795-826
pubmed: 21742788
J Am Soc Mass Spectrom. 2012 Mar;23(3):553-62
pubmed: 22203576
J Am Soc Mass Spectrom. 2005 Sep;16(9):1493-1497
pubmed: 16019223
Anal Chem. 1991 Dec 15;63(24):1193A-1203A
pubmed: 1789447
J Am Soc Mass Spectrom. 2009 Mar;20(3):341-8
pubmed: 19110440
Curr Opin Chem Biol. 2018 Feb;42:93-100
pubmed: 29207278
J Am Chem Soc. 2011 May 18;133(19):7240-3
pubmed: 21517093
Biochemistry. 2020 Feb 18;59(6):742-754
pubmed: 31922743
Ups J Med Sci. 2011 May;116(2):81-9
pubmed: 21486192
Mass Spectrom Rev. 2019 May;38(3):291-320
pubmed: 30707468
Anal Chem. 2019 Jul 2;91(13):8564-8573
pubmed: 31141659
J Am Chem Soc. 2014 Jan 15;136(2):660-70
pubmed: 24372466
Nat Chem. 2009 Jul;1(4):326-31
pubmed: 20703363
Anal Chem. 2006 Apr 15;78(8):2802-9
pubmed: 16615796
Curr Opin Struct Biol. 2019 Feb;54:50-58
pubmed: 30743182
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Dec 1;67(Pt 12):1492-7
pubmed: 22139150
Biochem Soc Trans. 2020 Dec 18;48(6):2457-2466
pubmed: 33336686
FEBS J. 2006 Aug;273(15):3614-24
pubmed: 16884500
Nature. 1994 Apr 21;368(6473):756-60
pubmed: 8152488
J Am Soc Mass Spectrom. 2007 Feb;18(2):322-31
pubmed: 17084091
Anal Chem. 2019 Jun 18;91(12):7554-7561
pubmed: 31117399
Angew Chem Int Ed Engl. 2003 Oct 20;42(40):4900-4
pubmed: 14579433
PLoS Pathog. 2019 Jan 22;15(1):e1007537
pubmed: 30668586
Anal Chem. 2018 Aug 7;90(15):8865-8872
pubmed: 29956914
FEBS Lett. 2013 Apr 17;587(8):1106-18
pubmed: 23380070
Nat Struct Mol Biol. 2020 Jul;27(7):660-667
pubmed: 32541895
J Am Soc Mass Spectrom. 2019 Jun;30(6):932-945
pubmed: 30980379
Org Lett. 2010 Nov 5;12(21):4848-51
pubmed: 20931985
Angew Chem Int Ed Engl. 2014 Aug 25;53(35):9209-12
pubmed: 24990104
Biochemistry. 2007 Nov 27;46(47):13505-22
pubmed: 17979302
Nature. 2020 Feb;578(7794):273-277
pubmed: 32025029
Protein Sci. 2015 Aug;24(8):1301-12
pubmed: 26011795
Biophys J. 2020 Mar 10;118(5):1142-1151
pubmed: 32105649
Curr Opin Chem Biol. 2018 Feb;42:51-59
pubmed: 29154177

Auteurs

Charles Eldrid (C)

Institute of Structural and Molecular Biology, Division of Bioscience, University College London, London, WC1E 6BT, U.K.

Aisha Ben-Younis (A)

Institute of Structural and Molecular Biology, Division of Bioscience, University College London, London, WC1E 6BT, U.K.

Jakub Ujma (J)

Waters Corporation, Wilmslow SK9 4AX, U.K.

Hannah Britt (H)

Institute of Structural and Molecular Biology, Division of Bioscience, University College London, London, WC1E 6BT, U.K.

Tristan Cragnolini (T)

Institute of Structural and Molecular Biology, Birkbeck College, University of London, London WC1E 7HX, U.K.

Symeon Kalfas (S)

Institute of Structural and Molecular Biology, Division of Bioscience, University College London, London, WC1E 6BT, U.K.

Dale Cooper-Shepherd (D)

Waters Corporation, Wilmslow SK9 4AX, U.K.

Nick Tomczyk (N)

Waters Corporation, Wilmslow SK9 4AX, U.K.

Kevin Giles (K)

Waters Corporation, Wilmslow SK9 4AX, U.K.

Mike Morris (M)

Waters Corporation, Wilmslow SK9 4AX, U.K.

Rehana Akter (R)

Department of Chemistry, Stony Brook University, 100 Nicolls Road, Stony Brook, New York 11794, United States.

Daniel Raleigh (D)

Institute of Structural and Molecular Biology, Division of Bioscience, University College London, London, WC1E 6BT, U.K.
Department of Chemistry, Stony Brook University, 100 Nicolls Road, Stony Brook, New York 11794, United States.

Konstantinos Thalassinos (K)

Institute of Structural and Molecular Biology, Division of Bioscience, University College London, London, WC1E 6BT, U.K.
Institute of Structural and Molecular Biology, Birkbeck College, University of London, London WC1E 7HX, U.K.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH