Implementation of different HIV self-testing models with implications for HIV testing services during the COVID-19 pandemic: study protocol for secondary data analysis of the STAR Initiative in South Africa.


Journal

BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874

Informations de publication

Date de publication:
18 05 2021
Historique:
entrez: 19 5 2021
pubmed: 20 5 2021
medline: 22 5 2021
Statut: epublish

Résumé

HIV self-testing (HIVST) presents a convenient, private approach that removes barriers to providing HIV testing services. The Self-Testing Africa (STAR) Initiative aims to scale up HIVST among priority and undertested populations. HIVST has the potential to help maintain testing services during the social distancing restrictions implemented to prevent the spread of COVID-19. This project evaluates linkage to confirmatory testing and treatment for HIV-positive clients for the STAR South Africa site. This secondary data analysis protocol aims to evaluate different HIVST distribution models from a prospective study implemented during November 2017 and December 2020 by Ezintsha, a subdivision of Wits Reproductive Health and HIV Institute. Routinely collected distribution and self-reported HIVST outcomes data will be deidentified and analysed. The main outcomes of interest are linkage to care and treatment among HIVST users who report a reactive HIVST result. Additionally, we plan to determine sociodemographic factors associated with linkage to care and treatment among HIVST users. Descriptive statistics will be used to describe the variables of interest, and modified Poisson regression with robust variance estimation will be performed to identify factors associated with linkage to care and treatment among HIVST users who report a reactive HIVST result. Risk ratios and 95% CIs for the risk ratios will be reported. The study protocol has been approved by the University of Witwatersrand Human Research Ethics Committee. The dissemination plan for the study findings will include presentations to local and international health authorities, international conferences and publications in open access journals.

Identifiants

pubmed: 34006558
pii: bmjopen-2020-048585
doi: 10.1136/bmjopen-2020-048585
pmc: PMC8130734
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e048585

Subventions

Organisme : World Health Organization
ID : 001
Pays : International
Organisme : NIMH NIH HHS
ID : R00 MH110343
Pays : United States
Organisme : NIMH NIH HHS
ID : R25 MH080665
Pays : United States
Organisme : NIMH NIH HHS
ID : K99 MH110343
Pays : United States

Informations de copyright

© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Références

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pubmed: 32488552
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Auteurs

Mohammed Majam (M)

Ezintsha, a sub-division of Wits Reproductive Health and HIV Institute, University of Witwatersrand, Johannesburg, South Africa mmajam@wrhi.ac.za.
School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, Guateng, South Africa.

Donaldson F Conserve (DF)

Department of Prevention and Community Health, Milken Institute School of Public Health, George Washington University, Washington, DC, USA.

Vincent Zishiri (V)

Ezintsha, a sub-division of Wits Reproductive Health and HIV Institute, University of Witwatersrand, Johannesburg, South Africa.

Zelalem T Haile (ZT)

Department of Social Medicine, Ohio University Heritage College of Osteopathic Medicine, Dublin, Ohio, USA.

Angela Tembo (A)

Ezintsha, a sub-division of Wits Reproductive Health and HIV Institute, University of Witwatersrand, Johannesburg, South Africa.

Jane Phiri (J)

Ezintsha, a sub-division of Wits Reproductive Health and HIV Institute, University of Witwatersrand, Johannesburg, South Africa.

Karin Hatzold (K)

Population Services International, Johannesburg, South Africa.

Cheryl C Johnson (CC)

Global HIV, Hepatitis and STI Programmes, World Health Organization, Geneva, Switzerland.

Francois Venter (F)

Ezintsha, a sub-division of Wits Reproductive Health and HIV Institute, University of Witwatersrand, Johannesburg, South Africa.
School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, Guateng, South Africa.

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