Effect of enteral zinc supplementation on growth and neurodevelopment of preterm infants: a systematic review and meta-analysis.


Journal

Journal of perinatology : official journal of the California Perinatal Association
ISSN: 1476-5543
Titre abrégé: J Perinatol
Pays: United States
ID NLM: 8501884

Informations de publication

Date de publication:
04 2022
Historique:
received: 08 01 2021
accepted: 30 04 2021
revised: 29 03 2021
pubmed: 20 5 2021
medline: 14 4 2022
entrez: 19 5 2021
Statut: ppublish

Résumé

To evaluate effect of enteral zinc supplementation on growth and neurodevelopmental outcomes of preterm infants. A systematic review and meta-analysis of randomized-controlled trials (RCTs) examining growth and neurodevelopmental outcomes after zinc supplementation in preterm infants. Of eight RCTs involving 742 infants included, seven reported growth anthropometrics at 3-6 months corrected age (CA) and two reported neurodevelopmental outcomes at 6-12 months CA. Zinc supplementation was associated with increased weight z-score (weighted mean difference (WMD) = 0.50; 95% CI 0.23-0.76, heterogeneity I Zinc supplementation may enhance weight gain and linear growth in preterm infants. There is a lack of data about relationship between zinc supplementation and neurodevelopment.

Identifiants

pubmed: 34006967
doi: 10.1038/s41372-021-01094-7
pii: 10.1038/s41372-021-01094-7
doi:

Substances chimiques

Zinc J41CSQ7QDS

Types de publication

Journal Article Meta-Analysis Review Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

430-439

Commentaires et corrections

Type : CommentIn

Informations de copyright

© 2021. The Author(s), under exclusive licence to Springer Nature America, Inc.

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Auteurs

Belal Alshaikh (B)

Neonatal Nutrition and Gastroenterology Program, University of Calgary, Calgary, AB, Canada. balshaik@ucalgary.ca.
Community Health Sciences, Institute of Public Health, Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. balshaik@ucalgary.ca.

Moaaz Abo Zeed (M)

McMaster University, Hamilton, AB, Canada.

Kamran Yusuf (K)

Neonatal Nutrition and Gastroenterology Program, University of Calgary, Calgary, AB, Canada.

Madhusudan Guin (M)

Neonatal Nutrition and Gastroenterology Program, University of Calgary, Calgary, AB, Canada.

Tanis Fenton (T)

Community Health Sciences, Institute of Public Health, Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Nutrition Services, Alberta Health Services, Calgary, AB, Canada.

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