The Effect of Sodium Selenite on Expression of Mitochondrial Transcription Factor A during
Gene expression
In vitro oocyte maturation
Mice
Mitochondrial transcription factor A
Oocytes
Sodium selenite
Journal
Avicenna journal of medical biotechnology
ISSN: 2008-2835
Titre abrégé: Avicenna J Med Biotechnol
Pays: Iran
ID NLM: 101511065
Informations de publication
Date de publication:
Historique:
entrez:
20
5
2021
pubmed:
21
5
2021
medline:
21
5
2021
Statut:
ppublish
Résumé
The aim of the present study was to investigate the effect of Sodium Selenite (SS) supplemented media on oocyte maturation, expression of mitochondrial transcription factor A (TFAM) and embryo quality. Mouse Germinal Vesicle (GV) oocytes were collected after administration of Pregnant Mare Serum Gonadotropin (PMSG); in experimental group 1, oocytes were cultured and then subjected for The oocyte maturation rate to MII stage in SS treated group was significantly higher than non-treated oocytes (75.65 Supplementation of oocyte maturation culture media with SS improved the development rate of oocytes and embryo and also enhanced
Sections du résumé
BACKGROUND
BACKGROUND
The aim of the present study was to investigate the effect of Sodium Selenite (SS) supplemented media on oocyte maturation, expression of mitochondrial transcription factor A (TFAM) and embryo quality.
METHODS
METHODS
Mouse Germinal Vesicle (GV) oocytes were collected after administration of Pregnant Mare Serum Gonadotropin (PMSG); in experimental group 1, oocytes were cultured and then subjected for
RESULTS
RESULTS
The oocyte maturation rate to MII stage in SS treated group was significantly higher than non-treated oocytes (75.65
CONCLUSION
CONCLUSIONS
Supplementation of oocyte maturation culture media with SS improved the development rate of oocytes and embryo and also enhanced
Identifiants
pubmed: 34012523
doi: 10.18502/ajmb.v13i2.5526
pii: AJMB-13-81
pmc: PMC8112142
doi:
Types de publication
Journal Article
Langues
eng
Pagination
81-86Informations de copyright
Copyright© 2021 Avicenna Research Institute.
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