Retreatment of Chronic Hepatitis C Infection: Real-World Regimens and Outcomes From National Treatment Programs in Three Low- and Middle-Income Countries.


Journal

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
ISSN: 1537-6591
Titre abrégé: Clin Infect Dis
Pays: United States
ID NLM: 9203213

Informations de publication

Date de publication:
11 02 2022
Historique:
received: 24 12 2020
pubmed: 21 5 2021
medline: 15 3 2022
entrez: 20 5 2021
Statut: ppublish

Résumé

Access to recommended second-line treatments is limited for patients who fail initial hepatitis C virus (HCV) therapy in low- and middle-income countries. Alternative regimens and associated outcomes are not well understood. Through a pooled analysis of national program data in Egypt, Georgia, and Myanmar, we observed SVR rates >90% for alternative retreatment regimens.

Identifiants

pubmed: 34014252
pii: 6279051
doi: 10.1093/cid/ciab461
pmc: PMC8835629
doi:

Substances chimiques

Antiviral Agents 0

Types de publication

Journal Article Meta-Analysis Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

513-516

Subventions

Organisme : United Kingdom Foreign, Commonwealth and Development Office
Organisme : Coalition for Global Hepatitis Elimination

Informations de copyright

© The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America.

Références

Hepatol Int. 2018 Jul;12(4):356-367
pubmed: 30030720
Hepatology. 2017 Oct;66(4):1083-1089
pubmed: 28498551
Aliment Pharmacol Ther. 2018 Apr;47(7):1023-1031
pubmed: 29377245
Expert Rev Gastroenterol Hepatol. 2018 Dec;12(12):1245-1250
pubmed: 30791789
J Viral Hepat. 2020 May;27(5):548-551
pubmed: 31894886
World J Hepatol. 2015 Dec 8;7(28):2792-810
pubmed: 26668691
J Hepatol. 2021 Jul;75(1):251-254
pubmed: 33652031
Clin Mol Hepatol. 2019 Dec;25(4):360-365
pubmed: 31042864
N Engl J Med. 2017 Jun 1;376(22):2134-2146
pubmed: 28564569
Adv Virol. 2020 Jul 24;2020:9075905
pubmed: 32774374

Auteurs

Caroline E Boeke (CE)

Clinton Health Access Initiative, Boston, Massachusetts, USA.

Lindsey Hiebert (L)

Coalition for Global Hepatitis Elimination, Task Force for Global Health, Decatur, Georgia, USA.

Imam Waked (I)

Hepatology Department, National Liver Institute, Menoufia University, Shebeen El Kom, Egypt.

Tengiz Tsertsvadze (T)

Infectious Diseases, AIDS, and Clinical Immunology Research Center, Tbilisi, Georgia.

Lali Sharvadze (L)

Hepatology Clinic Hepa, Tbilisi, Georgia.

Maia Butsashvili (M)

Clinic Neolab, Tbilisi, Georgia.

Mamuka Zakalashvili (M)

Clinic Mrcheveii, Tbilisi, Georgia.

Win Naing (W)

Yangon Speciality Hospital, Yangon, Myanmar.

Neil Gupta (N)

Partners in Health/ Inshuti Mu Buzima, Kigali, Rwanda.

Fredrick Kateera (F)

Partners in Health/ Inshuti Mu Buzima, Kigali, Rwanda.

Craig McClure (C)

Clinton Health Access Initiative, Boston, Massachusetts, USA.

John W Ward (JW)

Coalition for Global Hepatitis Elimination, Task Force for Global Health, Decatur, Georgia, USA.

Christian B Ramers (CB)

Clinton Health Access Initiative, Boston, Massachusetts, USA.

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