Topical Liposomal Ozonated Oil in Complicated Corneal Disease: A Report on Three Clinical Cases.
corneal trauma
corneal ulcers
corneal wound healing
infectious keratitis
ozonated oil
Journal
International medical case reports journal
ISSN: 1179-142X
Titre abrégé: Int Med Case Rep J
Pays: New Zealand
ID NLM: 101566269
Informations de publication
Date de publication:
2021
2021
Historique:
received:
23
03
2021
accepted:
19
04
2021
entrez:
21
5
2021
pubmed:
22
5
2021
medline:
22
5
2021
Statut:
epublish
Résumé
Infectious and traumatic corneal diseases require adequate therapy against infection and promote re-epithelialization. The appearance of multidrug-resistant bacterial strains, induced by excessive use of antibiotics in the treatment of infectious diseases, has urged researchers to study new antimicrobial formulations. Ozonated oils have demonstrated antiseptic (antibacterial, antifungal and antiviral) and reparative properties and can be proposed for the prevention and treatment of acute and chronic local infections, as an alternative to conventional topical antimicrobials. In ocular treatment, ozonated oil can exert tissue repair and anti-inflammatory and bactericidal activity. Moreover, its specific formulation makes it well tolerated and biocompatible with the ocular surface. Herein, we report on three cases of corneal inflammation (dendritic epithelial keratitis, corneal injuries caused by olive leaves, and neurotrophic corneal ulcer), treated with liposomal ozonated oil (Ozodrop
Identifiants
pubmed: 34017203
doi: 10.2147/IMCRJ.S311839
pii: 311839
pmc: PMC8131066
doi:
Types de publication
Case Reports
Langues
eng
Pagination
327-332Informations de copyright
© 2021 Passidomo et al.
Déclaration de conflit d'intérêts
The authors report no conflicts of interest in this work.
Références
Case Rep Ophthalmol. 2018 May 24;9(2):287-298
pubmed: 29928225
Surv Ophthalmol. 2012 Sep;57(5):448-62
pubmed: 22542912
Surv Ophthalmol. 2017 May - Jun;62(3):286-301
pubmed: 27890620
Curr Eye Res. 2018 Jul;43(7):873-881
pubmed: 29634373
Int Ophthalmol. 2020 Dec;40(12):3209-3215
pubmed: 32696102
Molecules. 2020 Aug 07;25(16):
pubmed: 32784722
P T. 2015 Apr;40(4):277-83
pubmed: 25859123
Med Gas Res. 2017 Oct 17;7(3):212-219
pubmed: 29152215
Br J Ophthalmol. 2021 Mar;105(3):328-333
pubmed: 32580955
Transl Vis Sci Technol. 2020 Jul 02;9(8):4
pubmed: 32855851
Eye (Lond). 2020 Dec;34(12):2219-2226
pubmed: 32843744
Eye Brain. 2018 Jun 28;10:37-45
pubmed: 29988739
J Korean Med Sci. 2009 Jun;24(3):368-74
pubmed: 19543419