The potential for vaccination-induced herd immunity against the SARS-CoV-2 B.1.1.7 variant.
Herd Immunity
SARS-CoV-2
seroprevalence
vaccination
Journal
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
ISSN: 1560-7917
Titre abrégé: Euro Surveill
Pays: Sweden
ID NLM: 100887452
Informations de publication
Date de publication:
05 2021
05 2021
Historique:
entrez:
21
5
2021
pubmed:
22
5
2021
medline:
26
5
2021
Statut:
ppublish
Résumé
We assess the feasibility of reaching the herd immunity threshold against SARS-CoV-2 through vaccination, considering vaccine effectiveness (VE), transmissibility of the virus and the level of pre-existing immunity in populations, as well as their age structure. If highly transmissible variants of concern become dominant in areas with low levels of naturally-acquired immunity and/or in populations with large proportions of < 15 year-olds, control of infection without non-pharmaceutical interventions may only be possible with a VE ≥ 80%, and coverage extended to children.
Identifiants
pubmed: 34018481
doi: 10.2807/1560-7917.ES.2021.26.20.2100428
pmc: PMC8138959
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/V027956/1
Pays : United Kingdom
Organisme : NINDS NIH HHS
ID : R01 NS110424
Pays : United States
Investigateurs
Sam Abbott
(S)
W John Edmunds
(WJ)
Nicholas G Davies
(NG)
Rosalind M Eggo
(RM)
Graham Medley
(G)
Jiayao Lei
(J)
Yang Liu
(Y)
Damien C Tully
(DC)
Ciara V McCarthy
(CV)
Paul Mee
(P)
Akira Endo
(A)
Joel Hellewell
(J)
Sebastian Funk
(S)
Thibaut Jombart
(T)
Yalda Jafari
(Y)
Oliver Brady
(O)
Kiesha Prem
(K)
Fabienne Krauer
(F)
Mihaly Koltai
(M)
Naomi R Waterlow
(NR)
Timothy W Russell
(TW)
Sophie R Meakin
(SR)
Kathleen O'Reilly
(K)
Nikos I Bosse
(NI)
William Waites
(W)
Emily S Nightingale
(ES)
Rachel Lowe
(R)
Yung-Wai Desmond Chan
(YD)
Katherine E Atkins
(KE)
Billy J Quilty
(BJ)
Frank G Sandmann
(FG)
Kevin van Zandvoort
(K)
C Julian Villabona-Arenas
(CJ)
Hamish P Gibbs
(HP)
James D Munday
(JD)
Anna M Foss
(AM)
Amy Gimma
(A)
Carl A B Pearson
(CAB)
Rosanna C Barnard
(RC)
Matthew Quaife
(M)
Fiona Yueqian Sun
(FY)
Alicia Rosello
(A)
Rachael Pung
(R)
Christopher I Jarvis
(CI)
Emilie Finch
(E)
Kaja Abbas
(K)
Samuel Clifford
(S)
Gwenan M Knight
(GM)
Simon R Procter
(SR)
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