Platinum Cyclooctadiene Complexes with Activity against Gram-positive Bacteria.
antibiotic
inorganic medicinal chemistry
metalloantibiotic
metals in medicine
platinum
Journal
ChemMedChem
ISSN: 1860-7187
Titre abrégé: ChemMedChem
Pays: Germany
ID NLM: 101259013
Informations de publication
Date de publication:
15 10 2021
15 10 2021
Historique:
received:
05
03
2021
pubmed:
22
5
2021
medline:
24
2
2022
entrez:
21
5
2021
Statut:
ppublish
Résumé
Antimicrobial resistance is a looming health crisis, and it is becoming increasingly clear that organic chemistry alone is not sufficient to continue to provide the world with novel and effective antibiotics. Recently there has been an increased number of reports describing promising antimicrobial properties of metal-containing compounds. Platinum complexes are well known in the field of inorganic medicinal chemistry for their tremendous success as anticancer agents. Here we report on the promising antibacterial properties of platinum cyclooctadiene (COD) complexes. Amongst the 15 compounds studied, the simplest compounds Pt(COD)X
Identifiants
pubmed: 34018686
doi: 10.1002/cmdc.202100157
pmc: PMC8596843
doi:
Substances chimiques
Alkadienes
0
Coordination Complexes
0
1,5-cyclooctadiene
1E1VVD385Z
Platinum
49DFR088MY
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
3165-3171Subventions
Organisme : Australian Research Council (ARC) DECRA fellowship
ID : DE180100929
Organisme : Swiss National Science Foundation
ID : P2ZHP2_177997
Pays : Switzerland
Organisme : Wellcome Trust Strategic Grant
ID : WT1104797/Z/14/Z
Organisme : DFG-core facility Molecule Archive
ID : 284178167
Organisme : Wellcome Trust
Pays : United Kingdom
Informations de copyright
© 2021 The Authors. ChemMedChem published by Wiley-VCH GmbH.
Références
Lancet Infect Dis. 2019 Feb;19(2):e40-e50
pubmed: 30337260
J Antibiot (Tokyo). 2020 Jun;73(6):329-364
pubmed: 32152527
Nat Rev Drug Discov. 2004 Nov;3(11):900-1
pubmed: 15558857
J Biol Chem. 1967 Mar 25;242(6):1347-52
pubmed: 5337590
J Med Chem. 2009 Nov 12;52(21):6752-6
pubmed: 19827778
Chemistry. 2020 Mar 2;26(13):2852-2858
pubmed: 31788867
Phys Chem Chem Phys. 2019 Nov 28;21(44):24429-24440
pubmed: 31674630
Nat Rev Cancer. 2021 Jan;21(1):37-50
pubmed: 33128031
J Med Chem. 2008 May 22;51(10):2871-8
pubmed: 18260614
Chem Sci. 2019 Oct 29;11(1):70-79
pubmed: 32110358
Chem Rev. 2019 Jan 23;119(2):1058-1137
pubmed: 30640441
Chem Sci. 2020 Aug 7;11(33):8928-8935
pubmed: 34123147
ACS Infect Dis. 2020 Jun 12;6(6):1302-1304
pubmed: 32527097
Chem Sci. 2020 Nov 12;11(48):12888-12917
pubmed: 34123239
ACS Infect Dis. 2020 Nov 13;6(11):2959-2969
pubmed: 32960047
Chem Rev. 2016 Mar 9;116(5):3436-86
pubmed: 26865551
Chemistry. 2021 May 6;27(26):7340-7350
pubmed: 33368662
Chemistry. 2013 Sep 16;19(38):12794-9
pubmed: 23918643
Nat Rev Drug Discov. 2015 Sep;14(9):587-8
pubmed: 26265313
Virulence. 2016 Apr 2;7(3):214-29
pubmed: 26730990
J Am Chem Soc. 2014 Jan 8;136(1):116-8
pubmed: 24364388
Chemistry. 2021 Jan 26;27(6):2021-2029
pubmed: 33231906
ACS Infect Dis. 2015 Jul 10;1(7):285-7
pubmed: 27622818
Commun Biol. 2021 Jan 19;4(1):7
pubmed: 33469147
Dalton Trans. 2018 Mar 12;47(11):3689-3692
pubmed: 29465721
Dalton Trans. 2013 Mar 7;42(9):3196-209
pubmed: 23233164
ChemMedChem. 2021 Oct 15;16(20):3165-3171
pubmed: 34018686
Metallomics. 2020 Oct 21;12(10):1563-1575
pubmed: 32856674
ACS Nano. 2019 May 28;13(5):5133-5146
pubmed: 30964642
BMC Res Notes. 2017 Aug 29;10(1):428
pubmed: 28851426
Future Med Chem. 2019 Jan;11(2):119-135
pubmed: 30644327
Chem Sci. 2020 Jul 30;11(33):8828-8838
pubmed: 34123136
Chem Sci. 2020 Feb 12;11(10):2627-2639
pubmed: 32206266
Org Lett. 2000 Jul 13;2(14):2105-8
pubmed: 10891241
Eur J Med Chem. 2020 Nov 1;205:112533
pubmed: 32739550
Bioorg Chem. 2019 Jul;88:102925
pubmed: 31003078