Systemic sarcoidosis reactions as a result of tumour necrosis factor-alpha treatment for patients with psoriasis.


Journal

Clinical and experimental dermatology
ISSN: 1365-2230
Titre abrégé: Clin Exp Dermatol
Pays: England
ID NLM: 7606847

Informations de publication

Date de publication:
Dec 2021
Historique:
accepted: 18 05 2021
pubmed: 23 5 2021
medline: 4 2 2022
entrez: 22 5 2021
Statut: ppublish

Résumé

The high efficacy and tolerability of biological therapies such as anti-tumour necrosis factor-alpha (TNF-α) have transformed outcomes for many inflammatory conditions. Conversely, a wide range of paradoxical reactions, including pulmonary, renal and ocular sarcoidosis secondary to TNF-α blocking agents in patients with severe psoriasis, has been reported. Sarcoid-like granulomatosis is one of these reactions, which may affect the pulmonary and cutaneous systems. Renal and ocular sarcoidosis, however, are less frequent and have unknown consequences. In this report, we present two cases of anti-TNF-α-induced sarcoidosis involving the pulmonary and renal systems.

Identifiants

pubmed: 34021925
doi: 10.1111/ced.14751
doi:

Substances chimiques

Tumor Necrosis Factor Inhibitors 0
Tumor Necrosis Factor-alpha 0
Adalimumab FYS6T7F842
Etanercept OP401G7OJC

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1548-1550

Informations de copyright

© 2021 British Association of Dermatologists.

Références

Decock A, Assche GV, Vermeire S et al. Sarcoidosis-like lesions: another paradoxical reaction to anti-TNF therapy? J Crohn Colitis 2017; 11: 378-83.
Wendling D, Prati C. Paradoxical effects of anti-TNF-α agents in inflammatory diseases. Exp Rev Clin Immunol 2014; 10: 159-69.
Thavarajah K, Wu P, Rhew EJ et al. Pulmonary complications of tumor necrosis factor-targeted therapy. Respir Med 2009; 103: 661-9.
Daïen CI, Monier A, Claudepierre P. Sarcoid-like granulomatosis in patients treated with tumor necrosis factor blockers: 10 cases. Rheumatology 2009; 48: 883-6.
Sandys V, Moloney B, Lane L et al. Granulomatous interstitial nephritis secondary to adalimumab therapy. Clin Kidney J 2018; 11: 219-21.
Toussirot E, Pertuiset E. TNFα blocking agents and sarcoidosis: an update. Rev Méd Interne 2010; 31: 828-37.
Hostettler KE, Studler U, Tamm M et al. Long-term treatment with infliximab in patients with sarcoidosis. Respiration 2012; 83: 218-24.
Pritchard C, Nadarajah K. Tumour necrosis factor alpha inhibitor treatment for sarcoidosis refractory to conventional treatments: a report of five patients. Ann Rheum Dis 2004; 63: 318-20.
Korsten P, Sweiss NJ, Nagorsnik U et al. Drug-induced granulomatous interstitial nephritis in a patient with ankylosing spondylitis during therapy with adalimumab. Am J Kidney Dis 2010; 56: 17-21.

Auteurs

A P Bewley (AP)

Department of Dermatology, Barts Health NHS Trust, London, UK.

S Maleki (S)

Centre for Postgraduate Medicine and Public Health, University of Hertfordshire, Hertfordshire, UK.

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Classifications MeSH