High larvicidal efficacy of yeast-encapsulated orange oil against Aedes aegypti strains from Brazil.


Journal

Parasites & vectors
ISSN: 1756-3305
Titre abrégé: Parasit Vectors
Pays: England
ID NLM: 101462774

Informations de publication

Date de publication:
22 May 2021
Historique:
received: 12 12 2020
accepted: 21 04 2021
entrez: 23 5 2021
pubmed: 24 5 2021
medline: 16 11 2021
Statut: epublish

Résumé

Botanical substances such as essential oils (EOs) have demonstrated insecticidal properties and are a valid option for vector control. However, free EOs are unreliable as mosquito larvicides due their easy degradation by environmental exposure to ultraviolet light and higher temperatures. Here, we assessed the efficacy of a mosquito larvicide based on orange oil in a yeast-based delivery system against Aedes aegypti strains with different resistance status towards chemical neurotoxic insecticides. This larvicide preparation was physicochemically characterized in a previous report. Larvae of four Ae. aegypti strains from different regions of Brazil and different resistance profiles for deltamethrin (pyrethroid) and temephos (organophosphate) were tested against yeast-encapsulated orange oil (YEOO) in laboratory conditions for measurement of LC YEOO was found to be a highly active larvicide (LC YEOO demonstrates high larvicidal activity against Ae. aegypti strains with resistant phenotypes for deltamethrin (PY) and temephos (OP). This larvicidal activity suggests the potential for the development of YEOO as an alternative intervention to synthetic insecticides in integrated vector management programs, for populations with resistance to commonly used insecticides.

Sections du résumé

BACKGROUND BACKGROUND
Botanical substances such as essential oils (EOs) have demonstrated insecticidal properties and are a valid option for vector control. However, free EOs are unreliable as mosquito larvicides due their easy degradation by environmental exposure to ultraviolet light and higher temperatures. Here, we assessed the efficacy of a mosquito larvicide based on orange oil in a yeast-based delivery system against Aedes aegypti strains with different resistance status towards chemical neurotoxic insecticides. This larvicide preparation was physicochemically characterized in a previous report.
METHODS METHODS
Larvae of four Ae. aegypti strains from different regions of Brazil and different resistance profiles for deltamethrin (pyrethroid) and temephos (organophosphate) were tested against yeast-encapsulated orange oil (YEOO) in laboratory conditions for measurement of LC
RESULTS RESULTS
YEOO was found to be a highly active larvicide (LC
CONCLUSION CONCLUSIONS
YEOO demonstrates high larvicidal activity against Ae. aegypti strains with resistant phenotypes for deltamethrin (PY) and temephos (OP). This larvicidal activity suggests the potential for the development of YEOO as an alternative intervention to synthetic insecticides in integrated vector management programs, for populations with resistance to commonly used insecticides.

Identifiants

pubmed: 34022935
doi: 10.1186/s13071-021-04733-2
pii: 10.1186/s13071-021-04733-2
pmc: PMC8140510
doi:

Substances chimiques

Insecticides 0
Oils, Volatile 0
Plant Oils 0
Pyrethrins 0
orange oil AKN3KSD11B
Temefos ONP3ME32DL

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

272

Subventions

Organisme : CDC HHS
ID : #200-2017-93140
Pays : United States

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Auteurs

Bruno Gomes (B)

Laboratório de Bioquímica E Fisiologia de Insetos, Instituto Oswaldo Cruz (IOC-Fiocruz), Rio de Janeiro, Brazil. gsilva.bruno@gmail.com.

Huarlen Ogélio (H)

Laboratório de Mosquitos Transmissores de Hematozoários, Instituto Oswaldo Cruz (IOC-Fiocruz), Rio de Janeiro, Brazil.

Fabiane Brant (F)

Laboratório de Bioquímica E Fisiologia de Insetos, Instituto Oswaldo Cruz (IOC-Fiocruz), Rio de Janeiro, Brazil.

Camila Jesus Pereira-Pinto (CJ)

Laboratório de Bioquímica E Fisiologia de Insetos, Instituto Oswaldo Cruz (IOC-Fiocruz), Rio de Janeiro, Brazil.

Michael J Workman (MJ)

Center for Global Health, University of New Mexico Health Sciences Center, Albuquerque, NM, USA.
Department of Chemical and Biological Engineering, University of New Mexico, Albuquerque, NM, USA.

Monique Costa (M)

Laboratório de Fisiologia E Controle de Artrópodes Vetores, Oswaldo Cruz Institute - Oswaldo Cruz Foundation (IOC-FIOCRUZ), Rio de Janeiro, Brazil.

José Bento Pereira Lima (JBP)

Laboratório de Fisiologia E Controle de Artrópodes Vetores, Oswaldo Cruz Institute - Oswaldo Cruz Foundation (IOC-FIOCRUZ), Rio de Janeiro, Brazil.

Ademir Jesus Martins (AJ)

Laboratório de Fisiologia E Controle de Artrópodes Vetores, Oswaldo Cruz Institute - Oswaldo Cruz Foundation (IOC-FIOCRUZ), Rio de Janeiro, Brazil.
Instituto Nacional de Ciência E Tecnologia Em Entomologia Molecular, Rio de Janeiro, Brazil.

Marcelo Ramalho-Ortigao (M)

Department of Preventive Medicine and Biostatistics, Uniformed Services University, Bethesda, MD, USA.

Ravi Durvasula (R)

Loyola University Stritch School of Medicine, Maywood, IL, USA.

Ivy Hurwitz (I)

Center for Global Health, University of New Mexico Health Sciences Center, Albuquerque, NM, USA.

Mariana Rocha David (MR)

Laboratório de Mosquitos Transmissores de Hematozoários, Instituto Oswaldo Cruz (IOC-Fiocruz), Rio de Janeiro, Brazil.

Fernando Ariel Genta (FA)

Laboratório de Bioquímica E Fisiologia de Insetos, Instituto Oswaldo Cruz (IOC-Fiocruz), Rio de Janeiro, Brazil. gentafernando@gmail.com.
Instituto Nacional de Ciência E Tecnologia Em Entomologia Molecular, Rio de Janeiro, Brazil. gentafernando@gmail.com.

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