Translational biotechnology for the control of ticks and tick-borne diseases.
Omics
Paratransgenesis
Quantum vaccinology
Tick
Translational biotechnology
Vaccine
Journal
Ticks and tick-borne diseases
ISSN: 1877-9603
Titre abrégé: Ticks Tick Borne Dis
Pays: Netherlands
ID NLM: 101522599
Informations de publication
Date de publication:
09 2021
09 2021
Historique:
received:
08
04
2021
revised:
03
05
2021
accepted:
03
05
2021
pubmed:
24
5
2021
medline:
8
9
2021
entrez:
23
5
2021
Statut:
ppublish
Résumé
Ticks and tick-borne diseases (TBD) represent a challenge for human and animal health worldwide. Climate change, distribution of tick hosts, and ecological and anthropogenically-induced changes contribute to the geographic expansion of ticks and tick-borne pathogens. Traditional control methods are based on the use of acaricides to reduce tick infestations, but vaccines represent a more effective, sustainable and environmentally sound approach for the control of ticks and TBD. Recent application of omics technologies to the study of the mechanisms involved in tick-host-pathogen interactions have advanced the characterization of molecular mechanisms involved in TBD and the identification of candidate vaccine protective antigens. However, as discussed in this opinion paper, translational biotechnology may translate into novel interventions required to advance in addressing the challenge that ticks and TBD represent for world health and economy.
Identifiants
pubmed: 34023540
pii: S1877-959X(21)00091-1
doi: 10.1016/j.ttbdis.2021.101738
pii:
doi:
Substances chimiques
Acaricides
0
Vaccines
0
Types de publication
Editorial
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
101738Informations de copyright
Copyright © 2021. Published by Elsevier GmbH.