Pathophysiology, Diagnosis, and Management of Coronary No-Reflow Phenomenon.
angiogram
diagnosis
magnetic resonance imaging
management
no-reflow phenomenon
pathophysiology
Journal
The International journal of angiology : official publication of the International College of Angiology, Inc
ISSN: 1061-1711
Titre abrégé: Int J Angiol
Pays: United States
ID NLM: 9504821
Informations de publication
Date de publication:
Mar 2021
Mar 2021
Historique:
entrez:
24
5
2021
pubmed:
25
5
2021
medline:
25
5
2021
Statut:
ppublish
Résumé
Coronary no-reflow phenomenon is a lethal mechanism of ongoing myocardial injury, following successful revascularization of an infarct-related coronary artery. Incidence of this phenomenon is high following percutaneous intervention, and is associated with adverse in-hospital and long-term outcomes. Several mechanisms such as ischemia-reperfusion injury and distal microthromboembolism in genetically susceptible patients and those with preexisting endothelial dysfunction have been implicated. However, the exact mechanism in humans is still poorly understood. Several investigative and treatment strategies within and outside the cardiac catheterization laboratory have been proposed, but have not uniformly shown success in reducing mortality or in preventing adverse left ventricular remodeling resulting from this condition. The aim of this article is to provide a brief and concise review of the current understanding of the pathophysiology, clinical predictors, and investigations and management of coronary no-reflow phenomenon.
Identifiants
pubmed: 34025092
doi: 10.1055/s-0041-1725979
pii: 200117
pmc: PMC8128485
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
15-21Informations de copyright
International College of Angiology. This article is published by Thieme.
Déclaration de conflit d'intérêts
Conflict of Interest None declared.
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