Impairment of episodic memory in genetic frontotemporal dementia: A GENFI study.

cognition episodic memory executive function frontal lobe frontotemporal dementia genetic disorders neuropsychology temporal lobe voxel‐based morphometry

Journal

Alzheimer's & dementia (Amsterdam, Netherlands)
ISSN: 2352-8729
Titre abrégé: Alzheimers Dement (Amst)
Pays: United States
ID NLM: 101654604

Informations de publication

Date de publication:
2021
Historique:
received: 07 01 2021
revised: 06 03 2021
accepted: 09 03 2021
entrez: 24 5 2021
pubmed: 25 5 2021
medline: 25 5 2021
Statut: epublish

Résumé

We aimed to assess episodic memory in genetic frontotemporal dementia (FTD) with the Free and Cued Selective Reminding Test (FCSRT). The FCSRT was administered in 417 presymptomatic and symptomatic mutation carriers (181 chromosome 9 open reading frame 72 [ All symptomatic mutation carrier groups and presymptomatic The FCSRT detects presymptomatic deficits in

Identifiants

pubmed: 34027016
doi: 10.1002/dad2.12185
pii: DAD212185
pmc: PMC8116844
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e12185

Subventions

Organisme : Medical Research Council
ID : MC_UU_00024/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/M008525/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/M023664/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/T046015/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/J009482/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/L023784/2
Pays : United Kingdom

Investigateurs

Martin N Rossor (MN)
Nick C Fox (NC)
Jason D Warren (JD)
Katrina Moore (K)
Rhian Convery (R)
Imogen J Swift (IJ)
Rachelle Shafei (R)
Carolin Heller (C)
Emily Todd (E)
Arabella Bouzigues (A)
David Cash (D)
Ione Woollacott (I)
Henrik Zetterberg (H)
Annabel Nelson (A)
Jennifer Nicholas (J)
Rita Guerreiro (R)
Jose Bras (J)
David L Thomas (DL)
Simon Mead (S)
Lieke Meeter (L)
Jessica Panman (J)
Rick van Minkelen (R)
Myriam Barandiaran (M)
Begoña Indakoetxea (B)
Alazne Gabilondo (A)
Mikel Tainta (M)
Ana Gorostidi (A)
Miren Zulaica (M)
Alina Díez (A)
Jorge Villanua (J)
Sergi Borrego-Ecija (S)
Olives Jaume (O)
Albert Lladó (A)
Mircea Balasa (M)
Anna Antonell (A)
Nuria Bargallo (N)
Enrico Premi (E)
Stefano Gazzina (S)
Roberto Gasparotti (R)
Silvana Archetti (S)
Sandra Black (S)
Sara Mitchell (S)
Ekaterina Rogaeva (E)
Morris Freedman (M)
Ron Keren (R)
David Tang-Wai (D)
Hakan Thonberg (H)
Linn Öijerstedt (L)
Christin Andersson (C)
Vesna Jelic (V)
Andrea Arighi (A)
Chiara Fenoglio (C)
Elio Scarpini (E)
Giorgio Fumagalli (G)
Thomas Cope (T)
Carolyn Timberlake (C)
Timothy Rittman (T)
Christen Shoesmith (C)
Robart Bartha (R)
Rosa Rademakers (R)
Carlo Wilke (C)
Hans-Otto Karnarth (HO)
Benjamin Bender (B)
Rose Bruffaerts (R)
Philip Vandamme (P)
Mathieu Vandenbulcke (M)
Catarina B Ferreira (CB)
Gabriel Miltenberger (G)
Carolina Maruta (C)
Ana Verdelho (A)
Sónia Afonso (S)
Ricardo Taipa (R)
Paola Caroppo (P)
Giuseppe Di Fede (G)
Giorgio Giaccone (G)
Sara Prioni (S)
Veronica Redaelli (V)
Giacomina Rossi (G)
Pietro Tiraboschi (P)
Diana Duro (D)
Maria Rosario Almeida (MR)
Miguel Castelo-Branco (M)
Maria João Leitão (MJ)
Miguel Tabuas-Pereira (M)
Beatriz Santiago (B)
Serge Gauthier (S)
Pedro Rosa-Neto (P)
Michele Veldsman (M)
Paul Thompson (P)
Tobias Langheinrich (T)
Catharina Prix (C)
Tobias Hoegen (T)
Elisabeth Wlasich (E)
Sandra Loosli (S)
Sonja Schonecker (S)
Sarah Anderl-Straub (S)
Jolina Lombardi (J)
Nuria Bargalló (N)
Alberto Benussi (A)
Valentina Cantoni (V)
Maxime Bertoux (M)
Anne Bertrand (A)
Alexis Brice (A)
Agnès Camuzat (A)
Olivier Colliot (O)
Sabrina Sayah (S)
Aurélie Funkiewiez (A)
Daisy Rinaldi (D)
Gemma Lombardi (G)
Benedetta Nacmias (B)
Dario Saracino (D)
Valentina Bessi (V)
Camilla Ferrari (C)
Marta Cañada (M)
Vincent Deramecourt (V)
Gregory Kuchcinski (G)
Thibaud Lebouvier (T)
Sebastien Ourselin (S)
Cristina Polito (C)
Adeline Rollin (A)

Informations de copyright

© 2021 The Authors. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring published by Wiley Periodicals, LLC on behalf of Alzheimer's Association.

Déclaration de conflit d'intérêts

The authors have no conflicts of interest to declare.

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Auteurs

Jackie M Poos (JM)

Department of Neurology Erasmus Medical Center Rotterdam the Netherlands.
Dementia Research Centre Department of Neurodegenerative Disease UCL Queen Square Institute of Neurology London UK.

Lucy L Russell (LL)

Dementia Research Centre Department of Neurodegenerative Disease UCL Queen Square Institute of Neurology London UK.

Georgia Peakman (G)

Dementia Research Centre Department of Neurodegenerative Disease UCL Queen Square Institute of Neurology London UK.

Martina Bocchetta (M)

Dementia Research Centre Department of Neurodegenerative Disease UCL Queen Square Institute of Neurology London UK.

Caroline V Greaves (CV)

Dementia Research Centre Department of Neurodegenerative Disease UCL Queen Square Institute of Neurology London UK.

Lize C Jiskoot (LC)

Department of Neurology Erasmus Medical Center Rotterdam the Netherlands.
Dementia Research Centre Department of Neurodegenerative Disease UCL Queen Square Institute of Neurology London UK.

Emma L van der Ende (EL)

Department of Neurology Erasmus Medical Center Rotterdam the Netherlands.

Harro Seelaar (H)

Department of Neurology Erasmus Medical Center Rotterdam the Netherlands.

Janne M Papma (JM)

Department of Neurology Erasmus Medical Center Rotterdam the Netherlands.

Esther van den Berg (E)

Department of Neurology Erasmus Medical Center Rotterdam the Netherlands.

Yolande A L Pijnenburg (YAL)

Department of Neurology Alzheimer Center Location VU University Medical Center Amsterdam Amsterdam the Netherlands.

Barbara Borroni (B)

Centre for Neurodegenerative Disorders Department of Clinical and Experimental Sciences University of Brescia Brescia Italy.

Raquel Sanchez-Valle (R)

Alzheimer's Disease and Other Cognitive Disorders Unit Neurology Service Hospital Clínic Institut d'Investigacións Biomèdiques August Pi I Sunyer University of Barcelona Barcelona Spain.

Fermin Moreno (F)

Cognitive Disorders Unit Department of Neurology Donostia University Hospital San Sebastian Gipuzkoa Spain.
Neuroscience Area Biodonostia Health Research Institute San Sebastian Gipuzkoa Spain.

Robert Laforce (R)

Clinique Interdisciplinaire de Mémoire Département des Sciences Neurologiques CHU de Québec Faculté de Médecine Université Laval Quebec Canada.

Caroline Graff (C)

Center for Alzheimer Research, Division of Neurogeriatrics Department of Neurobiology, Care Sciences and Society Bioclinicum Karolinska Institutet Solna Sweden.
Unit for Hereditary Dementias Theme Aging Karolinska University Hospital Solna Sweden.

Matthias Synofzik (M)

Department of Neurodegenerative Diseases Hertie-Institute for Clinical Brain Research and Center of Neurology University of Tübingen Tübingen Germany.
Center for Neurodegenerative Diseases (DZNE) Tübingen Germany.

Daniela Galimberti (D)

Department of Biomedical, Surgical and Dental Sciences University of Milan Milan Italy.
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Milan Italy.

James B Rowe (JB)

Department of Clinical Neurosciences Cambridge University Hospitals NHS Trust Medical Research Council Cognition and Brain Sciences Unit University of Cambridge Cambridge UK.

Mario Masellis (M)

Sunnybrook Health Sciences Centre Sunnybrook Research Institute University of Toronto Toronto Canada.

Carmela Tartaglia (C)

Tanz Centre for Research in Neurodegenerative Diseases University of Toronto Toronto Canada.

Elizabeth Finger (E)

Department of Clinical Neurological Sciences University of Western Ontario London Canada.

Rik Vandenberghe (R)

Laboratory for Cognitive Neurology Department of Neurosciences KU Leuven Leuven Belgium.
Neurology Service University Hospitals Leuven Leuven Belgium.
Leuven Brain Institute KU Leuven Leuven Belgium.

Alexandre de Medonça (A)

Laboratory of Neurosciences Institute of Molecular Medicine Faculty of Medicine University of Lisbon Lisbon Portugal.

Fabrizio Tagliavini (F)

Fondazione IRCCS Istituto Neurologico Carlo Besta Milan Italy.

Chris R Butler (CR)

Nuffield Department of Clinical Neurosciences Medical Sciences Division University of Oxford Oxford UK.
Department of Brain Sciences Imperial College London London UK.

Isabel Santana (I)

University Hospital of Coimbra (HUC) Neurology Service Faculty of Medicine University of Coimbra Coimbra Portugal.
Center for Neuroscience and Cell Biology Faculty of Medicine University of Coimbra Coimbra Portugal.

Isabelle Le Ber (IL)

Sorbonne Université Institut du Cerveau (ICM) INSERM U1127 CNRS UMR 7225 APHP Hôpital Pitié-Salpêtrière Paris France.
Centre de référence des démences rares ou précoces IM2A Département de Neurologie AP-HP Hôpital Pitié-Salpêtrière Paris France.
Département de Neurologie AP-HP Hôpital Pitié-Salpêtrière Paris France.

Alex Gerhard (A)

Division of Neuroscience and Experimental Psychology Wolfson Molecular Imaging Centre University of Manchester, Manchester UK.
Departments of Geriatric Medicine and Nuclear Medicine University of Duisburg Essen Germany.

Simon Ducharme (S)

Douglas Mental Health University Institute Department of Psychiatry McGill University Montreal Canada.
McConnell Brain Imaging Centre Montreal Neurological Institute Department of Neurology & Neurosurgery McGill University Montreal Canada.

Johannes Levin (J)

Neurologische Klinik und Poliklinik Ludwig-Maximilians-Universität Munich Germany.
German Center for Neurodegenerative Diseases (DZNE) Munich Germany.
Munich Cluster of Systems Neurology Munich Germany.

Adrian Danek (A)

Neurologische Klinik und Poliklinik Ludwig-Maximilians-Universität Munich Germany.

Markus Otto (M)

Department of Neurology University of Ulm Ulm Germany.

Sandro Sorbi (S)

Department of Neurofarba University of Florence Firenze Italy.
IRCCS Fondazione Don Carlo Gnocchi Florence Italy.

Florence Pasquier (F)

University of Lille Lille France.
Inserm 1172 Lille France.
CHU CNR-MAJ Labex Distalz LiCEND Lille France.

John C van Swieten (JC)

Department of Neurology Erasmus Medical Center Rotterdam the Netherlands.

Jonathan D Rohrer (JD)

Dementia Research Centre Department of Neurodegenerative Disease UCL Queen Square Institute of Neurology London UK.

Classifications MeSH