Immature acute leukaemias: lessons from the haematopoietic roadmap.
ICGS
acute leukaemia
acute myeloid leukaemia
early thymic precursor-ALL
haematopoiesis
mixed-phenotype acute leukaemia
Journal
The FEBS journal
ISSN: 1742-4658
Titre abrégé: FEBS J
Pays: England
ID NLM: 101229646
Informations de publication
Date de publication:
08 2022
08 2022
Historique:
revised:
30
04
2021
received:
02
02
2021
accepted:
20
05
2021
pubmed:
25
5
2021
medline:
5
8
2022
entrez:
24
5
2021
Statut:
ppublish
Résumé
It is essential to relate the biology of acute leukaemia to normal blood cell development. In this review, we discuss how modern models of haematopoiesis might inform approaches to diagnosis and management of immature leukaemias, with a specific focus on T-lymphoid and myeloid cases. In particular, we consider whether next-generation analytical tools could provide new perspectives that could improve our understanding of immature blood cancer biology.
Types de publication
Journal Article
Review
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
4355-4370Subventions
Organisme : Medical Research Council
ID : MC_PC_17230
Pays : United Kingdom
Informations de copyright
© 2021 The Authors. The FEBS Journal published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies.
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