Complications in COVID-19 patients: Characteristics of pulmonary embolism.
CT
CTPA
Covid-19
D-dimer
Pulmonary embolism
Journal
Clinical imaging
ISSN: 1873-4499
Titre abrégé: Clin Imaging
Pays: United States
ID NLM: 8911831
Informations de publication
Date de publication:
Sep 2021
Sep 2021
Historique:
received:
02
04
2021
revised:
09
05
2021
accepted:
16
05
2021
pubmed:
25
5
2021
medline:
22
7
2021
entrez:
24
5
2021
Statut:
ppublish
Résumé
The purpose of this study is to evaluate chest CT imaging features, clinical characteristics, laboratory values of COVID-19 patients who underwent CTA for suspected pulmonary embolism. We also examined whether clinical, laboratory or radiological characteristics could be associated with a higher rate of PE. This retrospective study included 84 consecutive patients with laboratory-confirmed SARS-CoV-2 who underwent CTA for suspected PE. The presence and localization of PE as well as the type and extent of pulmonary opacities on chest CT exams were examined and correlated with the information on comorbidities and laboratory values for all patients. Of the 84 patients, pulmonary embolism was discovered in 24 patients. We observed that 87% of PE was found to be in lung parenchyma affected by COVID-19 pneumonia. Compared with no-PE patients, PE patients showed an overall greater lung involvement by consolidation (p = 0.02) and GGO (p < 0.01) and a higher level of D-Dimer (p < 0,01). Moreover, the PE group showed a lower level of saturation (p = 0,01) and required more hospitalization (p < 0,01). Our study showed a high incidence of PE in COVID-19 pneumonia. In 87% of patients, PE was found in lung parenchyma affected by COVID-19 pneumonia with a worse CT severity score and a greater number of lung lobar involvement compared with non-PE patients. CT severity, lower level of saturation, and a rise in D-dimer levels could be an indication for a CTPA. Certain findings of non-contrast chest CT could be an indication for a CTPA.
Identifiants
pubmed: 34029929
pii: S0899-7071(21)00224-2
doi: 10.1016/j.clinimag.2021.05.016
pmc: PMC8130594
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
244-249Informations de copyright
Copyright © 2021 Elsevier Inc. All rights reserved.
Références
JAMA. 2020 Apr 7;323(13):1239-1242
pubmed: 32091533
Int J Cardiovasc Imaging. 2021 Apr;37(4):1349-1360
pubmed: 33211242
Nat Rev Dis Primers. 2018 May 17;4:18028
pubmed: 29770793
J Thromb Haemost. 2020 Apr;18(4):844-847
pubmed: 32073213
Thromb Res. 2020 Sep;193:86-89
pubmed: 32531548
Radiology. 2020 Nov;297(2):E270-E273
pubmed: 32437313
Radiol Cardiothorac Imaging. 2020 Feb 13;2(1):e200034
pubmed: 33778547
Thromb Res. 2020 Nov;195:95-99
pubmed: 32682004
Lancet Respir Med. 2020 Jul;8(7):681-686
pubmed: 32473124
Comput Biol Med. 2020 Sep;124:103960
pubmed: 32919186
J Am Coll Cardiol. 2020 Jun 16;75(23):2950-2973
pubmed: 32311448
J Thromb Haemost. 2005 Jan;3(1):93-9
pubmed: 15634271
Radiology. 2020 Aug;296(2):E41-E45
pubmed: 32049601
Lancet Respir Med. 2020 Apr;8(4):420-422
pubmed: 32085846
Int J Cardiol. 2020 Aug 15;313:129-131
pubmed: 32471650
JAMA. 2020 Mar 17;323(11):1061-1069
pubmed: 32031570
J Thorac Imaging. 2020 May;35(3):W90-W93
pubmed: 32195887
Eur J Radiol. 2020 Nov;132:109336
pubmed: 33069986
J Thromb Haemost. 2020 Jun;18(6):1421-1424
pubmed: 32271988
Thromb Res. 2020 Dec;196:541-542
pubmed: 33129037
Med Image Anal. 2021 Jan;67:101844
pubmed: 33091743
J Med Virol. 2020 Apr;92(4):401-402
pubmed: 31950516
Eur Radiol. 2020 Nov;30(11):6170-6177
pubmed: 32518989
Eur Heart J. 2020 May 14;41(19):1858
pubmed: 32227120
Clin Infect Dis. 2011 Jan 15;52(2):e14-7
pubmed: 21288835
AJR Am J Roentgenol. 2001 Jun;176(6):1415-20
pubmed: 11373204
AJR Am J Roentgenol. 2020 Jun;214(6):1280-1286
pubmed: 32130038
Blood. 2020 Jun 4;135(23):2033-2040
pubmed: 32339221
Thorax. 2005 Nov;60(11):956-61
pubmed: 16131526
Diagn Interv Imaging. 2020 May;101(5):325-326
pubmed: 32303472
Thromb Res. 2020 Jul;191:9-14
pubmed: 32353746
Radiology. 2020 Sep;296(3):E189-E191
pubmed: 32324102
Virchows Arch. 2020 Sep;477(3):349-357
pubmed: 32607684
Thromb Res. 2007;120(2):281-8
pubmed: 17030057
Thromb J. 2007 Oct 16;5:16
pubmed: 17939867
Eur Radiol. 2020 Aug;30(8):4407-4416
pubmed: 32215691
Thromb Res. 2020 Jun;190:58-59
pubmed: 32302782
Radiology. 2008 Mar;246(3):697-722
pubmed: 18195376
JAMA. 2020 Apr 28;323(16):1545-1546
pubmed: 32167538
Radiology. 2020 Oct;297(1):E216-E222
pubmed: 32324101
AJR Am J Roentgenol. 2020 May;214(5):1072-1077
pubmed: 32125873
Thromb Res. 2020 Jul;191:145-147
pubmed: 32291094
J Thorac Imaging. 2020 Nov 1;35(6):344-345
pubmed: 32349055
J Thromb Haemost. 2020 May;18(5):1094-1099
pubmed: 32220112
N Engl J Med. 2020 May 21;382(21):2012-2022
pubmed: 32227758
J Public Health Res. 2021 Apr 19;10(3):
pubmed: 33876627
Circulation. 2020 Jul 14;142(2):184-186
pubmed: 32330083
Respir Med. 2020 Aug;169:106023
pubmed: 32454268