Electrical behaviour and evolutionary computation in thin films of bovine brain microtubules.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
24 05 2021
Historique:
received: 11 03 2021
accepted: 12 04 2021
entrez: 25 5 2021
pubmed: 26 5 2021
medline: 9 11 2021
Statut: epublish

Résumé

We report on the electrical behaviour of thin films of bovine brain microtubules (MTs). For samples in both their dried and hydrated states, the measured currents reveal a power law dependence on the applied DC voltage. We attribute this to the injection of space-charge from the metallic electrode(s). The MTs are thought to form a complex electrical network, which can be manipulated with an applied voltage. This feature has been exploited to undertake some experiments on the use of the MT mesh as a medium for computation. We show that it is possible to evolve MT films into binary classifiers following an evolution in materio approach. The accuracy of the system is, on average, similar to that of early carbon nanotube classifiers developed using the same methodology.

Identifiants

pubmed: 34031499
doi: 10.1038/s41598-021-90260-0
pii: 10.1038/s41598-021-90260-0
pmc: PMC8144580
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

10776

Subventions

Organisme : Medical Research Council
Pays : United Kingdom

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Auteurs

Eléonore Vissol-Gaudin (E)

Department of Engineering, Durham University, South Road, Durham, DH1 3LE, UK.

Chris Pearson (C)

Department of Engineering, Durham University, South Road, Durham, DH1 3LE, UK.

Chris Groves (C)

Department of Engineering, Durham University, South Road, Durham, DH1 3LE, UK.

Dagou A Zeze (DA)

Department of Engineering, Durham University, South Road, Durham, DH1 3LE, UK.

Horacio F Cantiello (HF)

Laboratorio de Canales Iónicos, Instituto Multidisciplinario de Salud, Tecnología Y Desarrollo (IMSaTeD, CONICET-UNSE), Villa El Zanjón, 4206, Santiago del Estero, Argentina.

María Del Rocio Cantero (MDR)

Laboratorio de Canales Iónicos, Instituto Multidisciplinario de Salud, Tecnología Y Desarrollo (IMSaTeD, CONICET-UNSE), Villa El Zanjón, 4206, Santiago del Estero, Argentina.

Michael C Petty (MC)

Department of Engineering, Durham University, South Road, Durham, DH1 3LE, UK. m.c.petty@durham.ac.uk.

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Classifications MeSH