Reversible right-sided heart failure and pulmonary hypertension caused by scurvy in a 7-year-old boy with autism spectrum disorder and a review of the literature.

Pulmonary hypertension autism spectrum disorder iron deficiency right-sided heart failure vitamin C deficiency

Journal

Paediatrics and international child health
ISSN: 2046-9055
Titre abrégé: Paediatr Int Child Health
Pays: England
ID NLM: 101582666

Informations de publication

Date de publication:
25 May 2021
Historique:
entrez: 25 5 2021
pubmed: 26 5 2021
medline: 26 5 2021
Statut: aheadofprint

Résumé

Scurvy, a condition caused by vitamin C deficiency, is rare, especially in high-income countries. Symptoms of scurvy are typically characterised by dermatological disorders such as poor wound healing and tooth loss, but there is not usually cardiac involvement. A case of reversible pulmonary hypertension and right-sided heart failure owing to scurvy in a 7-year-old boy with autism spectrum disorder is reported. He had a very restricted diet and presented with polyarthralgia, gingival hyperplasia with ecchymosis, and fatigue. His condition, including pulmonary hypertension and right-sided heart failure, completely resolved with vitamin C supplementation. Paediatricians should have a high index of suspicion for scurvy in children with nutritional selectivity and be aware that it can manifest with cardiac symptoms. Scurvy may be life-threatening if not treated, but the symptoms can improve rapidly with vitamin C supplementation.

Identifiants

pubmed: 34033530
doi: 10.1080/20469047.2021.1901406
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-5

Auteurs

Keisuke Abe (K)

Department of Paediatrics, University of Hawaii, John A. Burns School of Medicine, Honolulu, HI, USA.

Rutuja Kibe (R)

Department of Paediatrics, University of Hawaii, John A. Burns School of Medicine, Honolulu, HI, USA.

Kurahara David (K)

Department of Paediatrics, University of Hawaii, John A. Burns School of Medicine, Honolulu, HI, USA.

Venu Reddy (V)

Department of Paediatrics, University of Hawaii, John A. Burns School of Medicine, Honolulu, HI, USA.

Bridget Allard (B)

Department of Paediatrics, Children's National Medical Center, Washington, DC, USA.

Marissa Fakaosita (M)

Department of Paediatrics, University of Hawaii, John A. Burns School of Medicine, Honolulu, HI, USA.

Classifications MeSH