Hyposplenism and Gastrointestinal Diseases: Significance and Mechanisms.
Coeliac disease
Hyposplenism
Inflammatory bowel disease
Spleen
Journal
Digestive diseases (Basel, Switzerland)
ISSN: 1421-9875
Titre abrégé: Dig Dis
Pays: Switzerland
ID NLM: 8701186
Informations de publication
Date de publication:
2022
2022
Historique:
received:
03
03
2021
accepted:
10
05
2021
pubmed:
26
5
2021
medline:
14
5
2022
entrez:
25
5
2021
Statut:
ppublish
Résumé
Functional hyposplenism is a recognized complication of several gastroenterological disorders, including coeliac and inflammatory bowel diseases, and is believed to contribute to the increased infection risk seen in these disorders. The mechanisms of hyposplenism are poorly understood. In this article, we review possible mechanisms underlying development of functional hyposplenism and discuss implications for its management. Identifying functional hyposplenism is important, as it may permit earlier recognition and treatment of serious infections through patient education and vaccination.
Sections du résumé
BACKGROUND
BACKGROUND
Functional hyposplenism is a recognized complication of several gastroenterological disorders, including coeliac and inflammatory bowel diseases, and is believed to contribute to the increased infection risk seen in these disorders.
SUMMARY
CONCLUSIONS
The mechanisms of hyposplenism are poorly understood. In this article, we review possible mechanisms underlying development of functional hyposplenism and discuss implications for its management.
KEY MESSAGES
CONCLUSIONS
Identifying functional hyposplenism is important, as it may permit earlier recognition and treatment of serious infections through patient education and vaccination.
Identifiants
pubmed: 34034254
pii: 000517338
doi: 10.1159/000517338
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
290-298Informations de copyright
© 2021 The Author(s). Published by S. Karger AG, Basel.