Estimating infectiousness throughout SARS-CoV-2 infection course.
Adolescent
Adult
Age Factors
Aged
Aged, 80 and over
Asymptomatic Infections
COVID-19
/ diagnosis
COVID-19 Nucleic Acid Testing
Caco-2 Cells
Child
Child, Preschool
Female
Germany
Hospitalization
Humans
Infant
Male
Middle Aged
Probability
SARS-CoV-2
/ isolation & purification
Viral Load
Virus Replication
Virus Shedding
Young Adult
Journal
Science (New York, N.Y.)
ISSN: 1095-9203
Titre abrégé: Science
Pays: United States
ID NLM: 0404511
Informations de publication
Date de publication:
09 07 2021
09 07 2021
Historique:
received:
15
03
2021
accepted:
21
05
2021
pubmed:
27
5
2021
medline:
23
7
2021
entrez:
26
5
2021
Statut:
ppublish
Résumé
Two elementary parameters for quantifying viral infection and shedding are viral load and whether samples yield a replicating virus isolate in cell culture. We examined 25,381 cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Germany, including 6110 from test centers attended by presymptomatic, asymptomatic, and mildly symptomatic (PAMS) subjects, 9519 who were hospitalized, and 1533 B.1.1.7 lineage infections. The viral load of the youngest subjects was lower than that of the older subjects by 0.5 (or fewer) log
Identifiants
pubmed: 34035154
pii: science.abi5273
doi: 10.1126/science.abi5273
pmc: PMC9267347
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : NIAID NIH HHS
ID : HHSN272201400008C
Pays : United States
Informations de copyright
Copyright © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.
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