From in vitro research to real life studies: an extensive narrative review of the effects of balneotherapy on human immune response.
Health resort therapy
Immune system
Mud therapy
Peloidotherapy
Spa therapy
Journal
Sport sciences for health
ISSN: 1824-7490
Titre abrégé: Sport Sci Health
Pays: Italy
ID NLM: 101256653
Informations de publication
Date de publication:
2021
2021
Historique:
received:
17
11
2020
accepted:
04
05
2021
pubmed:
27
5
2021
medline:
27
5
2021
entrez:
26
5
2021
Statut:
ppublish
Résumé
The biologic mechanisms by which balneotherapy (BT) alleviates symptoms of different diseases are still poorly understood. Recently, preclinical models and clinical trials have been developed to study the effects of BT on the immune system. This review summarizes the currently available evidence regarding the effects of spa therapy on the immune response, to confirm the role of BT in the enhancement of immune system and open interesting research fields. PubMed and Google Scholar were searched from 1997 up to June 2020, with search criteria including terms related to BT and immune system. We selected only in vitro research, randomized controlled trials (RCTs) or clinical trials. In vitro studies on human and animal samples have demonstrated that thermal waters exert anti-inflammatory and immunomodulatory effects. In particular, H Further preclinical studies and RCTs could help to exploit BT in real life for preventive and therapeutic treatments.
Identifiants
pubmed: 34035862
doi: 10.1007/s11332-021-00778-z
pii: 778
pmc: PMC8136372
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
817-835Informations de copyright
© The Author(s) 2021.
Déclaration de conflit d'intérêts
Conflict of interestThe authors declare that they have no conflict of interest.
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