Biomarkers of acute kidney injury in pediatric cardiac surgery.
Acute Kidney Injury
Biomarkers
Cardiac surgery
Children
Journal
Pediatric nephrology (Berlin, Germany)
ISSN: 1432-198X
Titre abrégé: Pediatr Nephrol
Pays: Germany
ID NLM: 8708728
Informations de publication
Date de publication:
01 2022
01 2022
Historique:
received:
13
01
2021
accepted:
23
04
2021
revised:
05
04
2021
pubmed:
27
5
2021
medline:
30
3
2022
entrez:
26
5
2021
Statut:
ppublish
Résumé
Acute kidney injury (AKI) is characterized by a sudden decrease in kidney function. Children with congenital heart disease are a special group at risk of developing AKI. We performed a systematic review of the literature to search for studies reporting the usefulness of novel urine, serum, and plasma biomarkers in the diagnosis and progression of AKI and their association with clinical outcomes in children undergoing pediatric cardiac surgery. In thirty studies, we analyzed the capacity to predict AKI and poor outcomes of five biomarkers: Cystatin C, Neutrophil gelatinase-associated lipocalin, Interleukin-18, Kidney injury molecule-1, and Liver fatty acid-binding protein. In conclusion, we suggest the need for further meta-analyses with the availability of additional studies.
Identifiants
pubmed: 34036445
doi: 10.1007/s00467-021-05094-9
pii: 10.1007/s00467-021-05094-9
doi:
Substances chimiques
Biomarkers
0
Types de publication
Journal Article
Review
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
61-78Commentaires et corrections
Type : CommentIn
Informations de copyright
© 2021. IPNA.
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