Irritability and Inattention Not Sad Low Mood Predict Impulsiveness in Children and Adolescents With Major Depressive Disorder and Persistent Depressive Disorder.
Journal
The Journal of nervous and mental disease
ISSN: 1539-736X
Titre abrégé: J Nerv Ment Dis
Pays: United States
ID NLM: 0375402
Informations de publication
Date de publication:
01 Jun 2021
01 Jun 2021
Historique:
entrez:
26
5
2021
pubmed:
27
5
2021
medline:
31
12
2021
Statut:
ppublish
Résumé
The specific relationships between impulsiveness, inattention, sad, low mood, and irritability have not been systematically examined in young people with major depressive disorder with and without persistent depressive disorder. The relationships are important to clarify because these symptom dimensions may increase suicidal risk in children and adolescents with these depressive disorders. A total of 313 medication-naive young people (aged 6-16 years) with active major depressive disorder (MDD) alone, persistent depressive disorder (DD) alone, and comorbid MDD and DD were identified. "Inattention," "sad/unhappy," and "irritable" mood were identified by parent standardized questionnaire. Standard multiple regression was used to investigate how well inattention, sad/unhappy, and irritable mood predict impulsiveness. Inattention (32% of the variance, increased) and irritable mood (5% of the variance, increased) both made independent significant contributions to impulsiveness, whereas sad/unhappy mood did not. Decreasing irritability via more targeted and comprehensive management approaches may ameliorate impulsiveness in young people with these depressive disorders.
Identifiants
pubmed: 34037553
doi: 10.1097/NMD.0000000000001293
pii: 00005053-202106000-00012
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
454-458Informations de copyright
Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.
Références
Achenbach T, Rescorla L (2001) Manual for the ASEBA school-age forms and profiles . Burlington, VT: University of Vermont.
American Psychiatric Association (2000) Diagnostic and Statistical Manual of Mental Disorders (4th ed, Text Revision ed). Washington, DC: American Psychiatric Association.
Angold A, Costello E (1993) Depressive comorbidity in children and adolescents: Empirical, theoretical and methodological issues. Am J Psych . 150:1779–1791.
Balbuena L, Bowen R, Baetz M, Marwaha S (2016) Mood instability and irritability as core symptoms of major depression: An exploration using Rasch analysis. Front Psychiatry . 7:174.
Bradvik L, Mattison C, Bogren M, Nettelbladt P (2008) Long-term suicide risk of depression in the Lundby cohort 1947–1997—Severity and gender. Acta Psych Scand . 117:185–191.
Braw Y, Aviram S, Bloch Y, Levkovitz Y (2011) The effect of age on frontal lobe related cognitive functions of unmedicated depressed patients. J Aff Dis . 129:342–347.
Brent D, Maalouf F (2009) Pediatric depression: Is there evidence to improve evidence-based treatments? J Child Psychol Psychiatry . 50:143–152.
Carver CS, Johnson SL, Joormann J (2013) Major depressive disorder and impulsive reactivity to emotion: Toward a dual-process view of depression. Br J Clin Psychol . 52:285–299.
Cataldo MG, Nobile M, Lorusso ML, Battaglia M, Molteni M (2005) Impulsivity in depressed children and adolescents: A comparison between behavioral and neuropsychological data. Psych Res . 136:123–133.
Chioqueta AP, Stiles T (2003) Suicide risk in outpatients with specific mood and anxiety disorders. Crisis . 24:105–112.
Conners CK (2008) Conners Rating Scales (3rd ed). New York: MHS.
Corruble E, Benyamina A, Bayle F, Fallisard B, Hardy P (2003) Understanding impulsivity in severe depression? A psychometric contribution. Prog Neuropsychopharm Biol Psychiatry . 27:829–833.
Fava M, Hwang I, Rush J, Sampson N, Walters E, Kessler R (2010) The importance of irritability as a symptom of major depressive disorder: Results from the national comorbidity survey replication. Mol Psych . 15:856–867.
Foley DL, Goldston DB, Costello EJ, Angold A (2006) Proximal psychiatric risk factors for suicidality in youth: The Great Smoky Mountain study. Arch Gen Psychiatry . 63:1017–1024.
Keller MB, Shapiro RW (1982) “Double depression”: The superimposition of acute depressive episodes on chronic depressive disorders. Am J Psychiatry . 139:438–442.
Kovacs M (1992) Children's Depression Inventory . Tonawanda, NY: Multi-Health Systems.
Kyte ZA, Goodyear IM, Sahakian BJ (2005) Selected executive skills in adolescents with recent first episode major depression. J Child Psychol Psych . 46:995–1005.
Lang M, Tisher M (2004) Children's Depression Scale (third ed). Melbourne: ACER.
Levitt A, Joffe R, MacDonald C (1991) Life course of depressive-illness and characteristics of current episode in patients with double depression. J Nerv Ment Dis . 179:678–682.
Liebenluft E (2017) Pediatric irritability: A systems neuroscience approach. Trends Cogn Sci . 21:277–289.
Maalouf F, Bakhti R, Tamin H, Shehab S, Brent D (2018) Neurocognitive predictors of clinical improvement in SSRI treated adolescents with major depressive disorder. J Child Adolesc Psychopharm . 28:387–394.
Madjar N, Shlosberg D, Leventer-Roberts M, Akriv A, Ghilai A, Hoshen M, Krivoy A, Zalsman G, Shoval G (2019) Childhood methylphenidate adherence as a predictor of antidepressants use during adolescence. Eur Child Adolesc Psychiatry . 28:1365–1373.
Porter R, Gallagher P, Thompson J, Young A (2003) Neurocognitive impairment in drug-free patients with major depressive disorder. Br J Psych . 182:214–220.
Rubia K, Hlari R, Christakou A, Taylor E (2009) Impulsiveness as a timing disturbance: Neurocognitive abnormalities in ADHD during temporal processes and normalisation with methylphenidate. Philos Trans R Soc Lond B Biol Sci . 364:1919–1931.
Sagvolden T, Sergeant JA (1998) Attention deficit hyperactivity disorder—From brain dysfunctions to behavior. Behav Brain Res . 94:1–10.
Shehab S, Brent D, Maalouf F (2016) Neurocognitive changes in SSRI-treated adolescents with depression. J Child Adolesc Psychopharm . 26:720.
Silverman WK, Albano AM (1996) Anxiety Disorders Interview Schedule for DSM-IV (ADISC) . Texas: Graywind.
Sonuga-Barke EJ, Brandeis D, Cortese S, Daley D, Ferrin M, Holtmann M, Stevenson J, Danckaerts M, van der Oord S, Döpfner M, Dittmann RW, Simonoff E, Zuddas A, Banaschewski T, Buitelaar J, Coghill D, Hollis C, Konofal E, Lecendreux M, Wong ICK, Sergeant J; European ADHD Guidelines Group (2013) Nonpharmacological interventions for ADHD: Systematic review and meta-analyses of randomized controlled trials of dietary and psychological treatments. Am J Psychiatry . 170:275–289.
Stanford MS, Greve KW, Dickens TJ (1995) Irritability and impulsiveness: Relationship to self-reported impulsive aggression. Pers Ind Diffs . 19:757–760.
Stringaris A, Maughan B, Copeland W, Costello E, Angold A (2013) Irritable mood as a symptom of depression in youth: Prevalence, developmental and clinical correlates in the Great Smoky Mountains study. J Am Acad Child Adolesc Psych . 52:831–840.
Swann A, Steinberg J, Lijffijt M, Moeller F (2008) Impulsivity: Differential relationship to depression and mania in bipolar disorder. J Aff Dis . 106:241–248.
Taylor E, Everitt B, Thorley G, Schachar R, Rutter M, Wieselberg M (1986) Conduct disorder and hyperactivity: II. A cluster analytic approach to the identification of a behavioural syndrome. Br J Psychiatry . 149:768–777.
Thomas SJ, Shin M, McInnis MG, Bostwick JR (2015) Combination therapy with monoamine oxidase inhibitors and other antidepressants or stimulants: Strategies for the management of treatment-resistant depression. Pharmaco . 35:433–449.
Van Meter A, Youngstrom E, Freeman A, Feeny N, Youngstrom J, Findling RL (2016) Impact of irritability and impulsive aggressive behavior on impairment and social functioning in youth with cyclothymic disorder. J Child Adolesc Psychoparmacol . 26:26–37.
Vance A, Ferrin M, Winther J, Gomez R (2013) Examination of spatial working memory performance in children and adolescents with ADHD combined type and anxiety. J Abn Child Psychol . 41:891–900.
Vance A, Sanders M, Arduca Y (2005) Dysthymic disorder contributes to oppositional defiant behavior in children with ADHD combined type. J Aff Dis . 86:229–233.
Vance A, Winther J (2020) Parent- and child-reported anxiety disorders differentiating major depressive disorder and dysthymic disorder in children and adolescents. Aust Psych . doi: 10.1177/1039856220960367.
doi: 10.1177/1039856220960367
Waslick B, Walsh B, Greenhill L, Eilenberg M, Capasso L, Lieber D (1999) Open trial of fluoxetine in children and adolescents with dysthymic disorder or double depression. J Affect Disord . 56:227–236.
Wechsler D (2003) Wechsler Intelligence Scale for Children—4th Edition (WISC-IV) . London: Pearson.
Werry J, Aman M, Diamond E (1980) Imipramine and methylphenidate in hyperactive children. J Child Psychol Psych . 21:27–35.
Wilkinson GS, Robertson GJ (2006) Wide Range Achievement Test, fourth edition (WRAT-4) . London: Pearson.
Witte TK, Timmons KA, Fink E, Smith AR, Joiner TE (2010) Do major depressive disorder and dysthymic disorder confer differential risk for suicide? J Aff Dis . 115:69–78.
Zisner A, Beauchaine TP (2016) Neural substrates of trait impulsivity, anhedonia and irritability: Mechanisms of heterotypic comorbidity between externalizing disorders and unipolar depression. Dev Psychopathol . 28:1177–1208.