Joint IARC/NCI International Cancer Seminar Series Report: expert consensus on future directions for ovarian carcinoma research.


Journal

Carcinogenesis
ISSN: 1460-2180
Titre abrégé: Carcinogenesis
Pays: England
ID NLM: 8008055

Informations de publication

Date de publication:
21 06 2021
Historique:
received: 18 02 2021
revised: 14 05 2021
accepted: 24 05 2021
pubmed: 27 5 2021
medline: 23 11 2021
entrez: 26 5 2021
Statut: ppublish

Résumé

Recently, ovarian cancer research has evolved considerably because of the emerging recognition that rather than a single disease, ovarian carcinomas comprise several different histotypes that vary by etiologic origin, risk factors, molecular profiles, therapeutic approaches and clinical outcome. Despite significant progress in our understanding of the etiologic heterogeneity of ovarian cancer, as well as important clinical advances, it remains the eighth most frequently diagnosed cancer in women worldwide and the most fatal gynecologic cancer. The International Agency for Research on Cancer and the United States National Cancer Institute jointly convened an expert panel on ovarian carcinoma to develop consensus research priorities based on evolving scientific discoveries. Expertise ranged from etiology, prevention, early detection, pathology, model systems, molecular characterization and treatment/clinical management. This report summarizes the current state of knowledge and highlights expert consensus on future directions to continue advancing etiologic, epidemiologic and prognostic research on ovarian carcinoma.

Identifiants

pubmed: 34037709
pii: 6284121
doi: 10.1093/carcin/bgab043
pmc: PMC8427725
doi:

Types de publication

Journal Article Research Support, N.I.H., Intramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

785-793

Subventions

Organisme : Medical Research Council
ID : MC_UU_00004/01
Pays : United Kingdom

Informations de copyright

Published by Oxford University Press 2021.

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Auteurs

Shama Virani (S)

International Agency for Research on Cancer (IARC/WHO), Genomic Epidemiology Branch, Lyon, France.

Glauco Baiocchi (G)

Department of Gynecology Oncology, A.C. Camargo Cancer Center, São Paulo, SP, Brazil.

David Bowtell (D)

Women's Cancer Program, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.

Citadel J Cabasag (CJ)

Cancer Surveillance Branch, International Agency for Research on Cancer, Lyon, France.

Kathleen R Cho (KR)

Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA.

Renée T Fortner (RT)

Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

Keiichi Fujiwara (K)

Department of Gynecologic Oncology, Saitama Medical University International Medical Center, Tokyo, Japan.

Jae-Weon Kim (JW)

Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Republic of Korea.

Martin Köbel (M)

Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Alberta, Canada.

Jean-Emmanuel Kurtz (JE)

Department of Medical and Surgical Oncology and Hematology, Strasbourg Cancer Institute (ICANS-Europe), Strasbourg, France.

Douglas A Levine (DA)

Gynecologic Oncology, Laura and Isaac Pearlmutter Cancer Center, New York University Langone Medical Center, New York, NY, USA.

Usha Menon (U)

MRC CTU at UCL, Institute of Clinical Trials and Methodology, University College London, London, UK.

Barbara M Norquist (BM)

Department of Obstetrics and Gynecology, University of Washington, Seattle, WA, USA.

Paul D P Pharoah (PDP)

Department of Oncology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

Anil K Sood (AK)

Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Shelley T Tworoger (ST)

Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.

Nicolas Wentzensen (N)

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, Bethesda, MD, USA.

Stephen J Chanock (SJ)

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, Bethesda, MD, USA.

Paul Brennan (P)

International Agency for Research on Cancer (IARC/WHO), Genomic Epidemiology Branch, Lyon, France.

Britton Trabert (B)

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, Bethesda, MD, USA.

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