High strength pure chitosan hydrogels via double crosslinking strategy.

Biocompatible Materials / chemistry Chitosan / chemistry Cross-Linking Reagents Hydrogels / chemistry Hydrophobic and Hydrophilic Interactions Materials Testing Tissue Engineering
chitosan double crosslinking high strength hydrogel tissue engineering

Journal

Biomedical materials (Bristol, England)
ISSN: 1748-605X
Titre abrégé: Biomed Mater
Pays: England
ID NLM: 101285195

Informations de publication

Date de publication:
28 06 2021
Historique:
received: 08 03 2021
accepted: 26 05 2021
pubmed: 27 5 2021
medline: 24 2 2022
entrez: 26 5 2021
Statut: epublish

Résumé

Chitosan (CS) hydrogels have been widely used throughout basic tissue engineering and regenerative medicine research and it is very desirable to develop advanced CS materials with superior mechanical and topographical properties for more extensive applications. Herein, we present the design of a double crosslinking pure CS hydrogel material via the synergic effect of the chemical covalent network, hydrophobic interactions, enhanced intermolecular hydrogen bonding and the formation of the CS crystallite. The resultant pure CS hydrogel possesses increases in strength and toughness by two orders of magnitude (fracture energy ∼7.733 J m

Identifiants

DOI: 10.1088/1748-605X/ac058c PMID: 34038891
pubmed: 34038891
doi: 10.1088/1748-605X/ac058c
doi:

Substances chimiques

Biocompatible Materials 0
Cross-Linking Reagents 0
Hydrogels 0
Chitosan 9012-76-4

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2021 IOP Publishing Ltd.

Auteurs

Lei Huang (L)

School of Nano-Tech and Nano-Bionics, University of Science and Technology of China, Hefei 230026, People's Republic of China.
Key Laboratory for Nano-Bio Interface Research, Division of Nanobiomedicine, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215123, People's Republic of China.

Yun Chu (Y)

School of Nano-Tech and Nano-Bionics, University of Science and Technology of China, Hefei 230026, People's Republic of China.
Key Laboratory for Nano-Bio Interface Research, Division of Nanobiomedicine, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215123, People's Republic of China.

Lulu Zhang (L)

School of Nano-Tech and Nano-Bionics, University of Science and Technology of China, Hefei 230026, People's Republic of China.
Key Laboratory for Nano-Bio Interface Research, Division of Nanobiomedicine, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215123, People's Republic of China.

Xiru Liu (X)

Key Laboratory for Nano-Bio Interface Research, Division of Nanobiomedicine, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215123, People's Republic of China.

Wangping Hao (W)

Key Laboratory for Nano-Bio Interface Research, Division of Nanobiomedicine, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215123, People's Republic of China.

Yanyan Chen (Y)

Key Laboratory for Nano-Bio Interface Research, Division of Nanobiomedicine, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215123, People's Republic of China.

Jianwu Dai (J)

Key Laboratory for Nano-Bio Interface Research, Division of Nanobiomedicine, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215123, People's Republic of China.
State Key Laboratory of Molecular Development Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, People's Republic of China.
ORCID: 0000-0002-3379-9053

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Classifications MeSH

questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomédicaux et dentaires › Matériaux biocompatibles › High strength pure chitosan hydrogels via...
questionsmedicales.fr › Glucides › Polyosides › Chitine › Chitosane › High strength pure chitosan hydrogels via...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Indicateurs et réactifs › Réactifs réticulants › High strength pure chitosan hydrogels via...
questionsmedicales.fr › Préparations pharmaceutiques › Colloïdes › Gels › Hydrogels › High strength pure chitosan hydrogels via...
questionsmedicales.fr › Phénomènes chimiques › Interactions hydrophobes et hydrophiles › High strength pure chitosan hydrogels via...
questionsmedicales.fr › Techniques d'investigation › Test de matériaux › High strength pure chitosan hydrogels via...
questionsmedicales.fr › Technologie, industrie et agriculture › Ingénierie › Bioingénierie › Ingénierie cellulaire › Ingénierie tissulaire › High strength pure chitosan hydrogels via...