Evaluating the utility of Rapid Response EEG in emergency care.

critical care transport emergency care systems emergency department management emergency departments epilepsy intensive care neurology

Journal

Emergency medicine journal : EMJ
ISSN: 1472-0213
Titre abrégé: Emerg Med J
Pays: England
ID NLM: 100963089

Informations de publication

Date de publication:
Dec 2021
Historique:
received: 09 11 2020
accepted: 11 05 2021
pubmed: 28 5 2021
medline: 15 12 2021
entrez: 27 5 2021
Statut: ppublish

Résumé

Timely management of non-convulsive status epilepticus (NCSE) is critical to improving patient outcomes. However, NCSE can only be confirmed using electroencephalography (EEG), which is either significantly delayed or entirely unavailable in emergency departments (EDs). We piloted the use of a new bedside EEG device, Rapid Response EEG (Rapid-EEG, Ceribell), in the ED and evaluated its impact on seizure management when used by emergency physicians. Patients who underwent Rapid-EEG to rule out NCSE were prospectively enrolled in a pilot project conducted at two ED sites (an academic hospital and a community hospital). Physicians were surveyed on the perceived impact of the device on seizure treatment and patient disposition, and we calculated physicians' sensitivity and specificity (with 95% CI) for diagnosing NCSE using Rapid-EEG's Of the 38 patients enrolled, the one patient with NCSE was successfully diagnosed and treated within minutes of evaluation. Physicians reported that Rapid-EEG changed clinical management for 20 patients (53%, 95% CI 37% to 68%), primarily by ruling out seizures and avoiding antiseizure treatment escalation, and expedited disposition for 8 patients (21%, 95% CI 11% to 36%). At the community site, physicians diagnosed seizures by their sound using Rapid-EEG was successfully deployed by emergency physicians at academic and community hospitals, and the device changed management in a majority of cases. Widespread adoption of Rapid-EEG may lead to earlier diagnosis of NCSE, reduced unnecessary treatment and expedited disposition of seizure mimics.

Sections du résumé

BACKGROUND BACKGROUND
Timely management of non-convulsive status epilepticus (NCSE) is critical to improving patient outcomes. However, NCSE can only be confirmed using electroencephalography (EEG), which is either significantly delayed or entirely unavailable in emergency departments (EDs). We piloted the use of a new bedside EEG device, Rapid Response EEG (Rapid-EEG, Ceribell), in the ED and evaluated its impact on seizure management when used by emergency physicians.
METHODS METHODS
Patients who underwent Rapid-EEG to rule out NCSE were prospectively enrolled in a pilot project conducted at two ED sites (an academic hospital and a community hospital). Physicians were surveyed on the perceived impact of the device on seizure treatment and patient disposition, and we calculated physicians' sensitivity and specificity (with 95% CI) for diagnosing NCSE using Rapid-EEG's
RESULTS RESULTS
Of the 38 patients enrolled, the one patient with NCSE was successfully diagnosed and treated within minutes of evaluation. Physicians reported that Rapid-EEG changed clinical management for 20 patients (53%, 95% CI 37% to 68%), primarily by ruling out seizures and avoiding antiseizure treatment escalation, and expedited disposition for 8 patients (21%, 95% CI 11% to 36%). At the community site, physicians diagnosed seizures by their sound using
CONCLUSION CONCLUSIONS
Rapid-EEG was successfully deployed by emergency physicians at academic and community hospitals, and the device changed management in a majority of cases. Widespread adoption of Rapid-EEG may lead to earlier diagnosis of NCSE, reduced unnecessary treatment and expedited disposition of seizure mimics.

Identifiants

pubmed: 34039642
pii: emermed-2020-210903
doi: 10.1136/emermed-2020-210903
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

923-926

Informations de copyright

© Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: KG serves as a scientific advisor and consultant to Ceribell Inc., which is commercialising Rapid Response EEG for clinical use.

Auteurs

Norah M K Wright (NMK)

Emergency Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, USA.

Evan S Madill (ES)

Neurology, Stanford University School of Medicine, Stanford, California, USA.

Derek Isenberg (D)

Emergency Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, USA.

Kapil Gururangan (K)

Neurology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Hannah McClellen (H)

Emergency Services, Stanford Health Care, Stanford, California, USA.

Samuel Snell (S)

Emergency Services, Stanford Health Care, Stanford, California, USA.

Mercedes P Jacobson (MP)

Neurology, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, USA.

Nina T Gentile (NT)

Emergency Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, USA.

Prasanthi Govindarajan (P)

Emergency Medicine, Stanford University School of Medicine, Stanford, California, USA pgovinda@stanford.edu.

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Classifications MeSH