Evaluation of Microdissection Testicular Sperm Extraction (mTESE), Outcomes and Predictive Factors in Ireland: The Gold Standard for Men with Non-Obstructive Azoospermia.
Male infertility
Microdissection testicular sperm extraction
Non-obstructive azoospermia
Predictive markers
Sperm retrieval
Journal
Journal of reproduction & infertility
ISSN: 2228-5482
Titre abrégé: J Reprod Infertil
Pays: Iran
ID NLM: 101535586
Informations de publication
Date de publication:
Historique:
entrez:
27
5
2021
pubmed:
28
5
2021
medline:
28
5
2021
Statut:
ppublish
Résumé
Microdissection testicular sperm extraction (mTESE) is the gold standard approach in sperm retrieval in men with non-obstructive azoospermia (NOA). The purpose of the study was to assess the outcomes for Irish men who have undergone mTESE with a single surgeon. This is a retrospective, single cohort study. Thirty-four patients underwent mTESE between September 2015 and June 2019. A p<0.05 was considered statistically significant. In this study, sperm retrieval rate (SRR) was 47.06%. (16/34). The mean age in those who had retrieved sperm at mTESE was 37.9±2.6 years. Johnson Score (JS) and FSH were statistically different between successful and unsuccessful mTESE groups (p=0.017*10 The combination of mTESE/Intracytoplasmic sperm injection (ICSI) is the best option available for men with NOA who prefer to achieve paternity using their own DNA. Given the overall SRRs in mTESE, it is imperative to continue research for a predictive model to better counsel azoospermic men regarding the use of mTESE. For this purpose, large, multicenter, randomized controlled trials are needed.
Sections du résumé
BACKGROUND
BACKGROUND
Microdissection testicular sperm extraction (mTESE) is the gold standard approach in sperm retrieval in men with non-obstructive azoospermia (NOA). The purpose of the study was to assess the outcomes for Irish men who have undergone mTESE with a single surgeon.
METHODS
METHODS
This is a retrospective, single cohort study. Thirty-four patients underwent mTESE between September 2015 and June 2019. A p<0.05 was considered statistically significant.
RESULTS
RESULTS
In this study, sperm retrieval rate (SRR) was 47.06%. (16/34). The mean age in those who had retrieved sperm at mTESE was 37.9±2.6 years. Johnson Score (JS) and FSH were statistically different between successful and unsuccessful mTESE groups (p=0.017*10
CONCLUSION
CONCLUSIONS
The combination of mTESE/Intracytoplasmic sperm injection (ICSI) is the best option available for men with NOA who prefer to achieve paternity using their own DNA. Given the overall SRRs in mTESE, it is imperative to continue research for a predictive model to better counsel azoospermic men regarding the use of mTESE. For this purpose, large, multicenter, randomized controlled trials are needed.
Identifiants
pubmed: 34041006
doi: 10.18502/jri.v22i2.5795
pii: JRI-22-103
pmc: PMC8143015
doi:
Types de publication
Journal Article
Langues
eng
Pagination
103-109Informations de copyright
Copyright© 2021, Avicenna Research Institute.
Déclaration de conflit d'intérêts
Conflict of Interest There are no conflicts of interest.
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