Clinical Efficacy of Follitropin Alfa in GnRH-Antagonist Protocols: A Prospective Observational Phase IV Study on the Use of Biosimilar Follitropin Alfa r-hFSH in Assisted Reproductive Technology in a Routine Care Setting.
Assisted reproductive technology
Biosimilar pharmaceuticals
Follitropin alfa
Gonadotropin-releasing hormone antagonist
Journal
Journal of reproduction & infertility
ISSN: 2228-5482
Titre abrégé: J Reprod Infertil
Pays: Iran
ID NLM: 101535586
Informations de publication
Date de publication:
Historique:
entrez:
27
5
2021
pubmed:
28
5
2021
medline:
28
5
2021
Statut:
ppublish
Résumé
This phase IV routine care study evaluated ovarian responses when using a biosimilar follitropin alfa r-hFSH (Bemfola This multicenter, prospective, non-comparative, non-interventional study (Germany/Austria) was conducted with 885 women (Mean age of 34.0±4.4 years) for whom COS with Bemfola Among 986 ART cycles, COS was given for 9.9±1.8 days (First-day r-hFSH dose of 220.7±68.9 COS with Bemfola
Sections du résumé
BACKGROUND
BACKGROUND
This phase IV routine care study evaluated ovarian responses when using a biosimilar follitropin alfa r-hFSH (Bemfola
METHODS
METHODS
This multicenter, prospective, non-comparative, non-interventional study (Germany/Austria) was conducted with 885 women (Mean age of 34.0±4.4 years) for whom COS with Bemfola
RESULTS
RESULTS
Among 986 ART cycles, COS was given for 9.9±1.8 days (First-day r-hFSH dose of 220.7±68.9
CONCLUSION
CONCLUSIONS
COS with Bemfola
Identifiants
pubmed: 34041008
doi: 10.18502/jri.v22i2.5798
pii: JRI-22-116
pmc: PMC8143010
doi:
Types de publication
Journal Article
Langues
eng
Pagination
116-124Informations de copyright
Copyright© 2021, Avicenna Research Institute.
Déclaration de conflit d'intérêts
Conflict of Interest The authors declare that they have no conflicts of interest.
Références
Hum Reprod. 2007 May;22(5):1348-52
pubmed: 17303632
JBRA Assist Reprod. 2017 Feb 1;21(1):49-53
pubmed: 28333033
Reprod Biomed Online. 2015 May;30(5):504-13
pubmed: 25735918
Hum Reprod. 2017 Dec 1;32(12):2485-2495
pubmed: 29121350
Expert Opin Drug Deliv. 2014 Dec;11(12):1859-64
pubmed: 25325925
Eur J Drug Metab Pharmacokinet. 2016 Jun;41(3):259-65
pubmed: 25633239
Fertil Steril. 2018 Jul 15;110(2):185-324.e5
pubmed: 30053940
Expert Opin Drug Deliv. 2018 Jun;15(6):549-558
pubmed: 29595399
Ultrasound Obstet Gynecol. 2015 Apr;45(4):377-93
pubmed: 25302750