Age-Dependent Remodeling in Infrapatellar Fat Pad Adipocytes and Extracellular Matrix: A Comparative Study.

aging anterior-cruciate ligament rupture cadaver donors extracellular matrix infrapatellar fat pad osteoarthritis

Journal

Frontiers in medicine
ISSN: 2296-858X
Titre abrégé: Front Med (Lausanne)
Pays: Switzerland
ID NLM: 101648047

Informations de publication

Date de publication:
2021
Historique:
received: 30 01 2021
accepted: 09 04 2021
entrez: 27 5 2021
pubmed: 28 5 2021
medline: 28 5 2021
Statut: epublish

Résumé

The infrapatellar fat pad (IFP) is actively involved in knee osteoarthritis (OA). However, a proper description of which developmental modifications occur in the IFP along with age and in absence of joint pathological conditions, is required to adequately describe its actual contribution in OA pathophysiology. Here, two IFP sources were compared: (a) IFP from healthy young patients undergoing anterior-cruciate ligament (ACL) reconstruction for ACL rupture (

Identifiants

pubmed: 34041253
doi: 10.3389/fmed.2021.661403
pmc: PMC8141643
doi:

Types de publication

Journal Article

Langues

eng

Pagination

661403

Informations de copyright

Copyright © 2021 Stocco, Belluzzi, Contran, Boscolo-Berto, Picardi, Guidolin, Fontanella, Olivotto, Filardo, Borile, Romanato, Ramonda, Ruggieri, Favero, Porzionato, De Caro and Macchi.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Références

J Cell Physiol. 2017 Aug;232(8):1971-1978
pubmed: 27925193
Arthritis Rheum. 2009 Nov;60(11):3374-7
pubmed: 19877065
Annu Rev Biochem. 2009;78:929-58
pubmed: 19344236
Cells Tissues Organs. 2016;201(3):220-31
pubmed: 26796341
Int J Cancer. 2016 Sep 1;139(5):1140-9
pubmed: 27116366
J Bodyw Mov Ther. 2020 Jan;24(1):138-146
pubmed: 31987534
J Biomed Opt. 2018 Mar;23(9):1-9
pubmed: 29516689
PLoS One. 2015 Dec 07;10(12):e0144525
pubmed: 26641456
BMC Bioinformatics. 2013 Aug 26;14:260
pubmed: 23971965
Curr Top Dev Biol. 2018;130:1-37
pubmed: 29853174
Ann Rheum Dis. 2011 May;70(5):851-7
pubmed: 21242232
Australas Phys Eng Sci Med. 2018 Sep;41(3):657-667
pubmed: 29943312
Sci Transl Med. 2012 Nov 14;4(160):160ps24
pubmed: 23152326
Acta Med Port. 2015 Jan-Feb;28(1):99-106
pubmed: 25817486
Nutrients. 2019 Oct 23;11(11):
pubmed: 31652734
Clin Anat. 2020 Sep;33(6):950-959
pubmed: 32427400
J Mech Behav Biomed Mater. 2017 Mar;67:1-9
pubmed: 27936429
Methods Mol Biol. 2017;1627:409-425
pubmed: 28836217
Biosci Rep. 2016 Jul 15;36(4):
pubmed: 27247426
J Cachexia Sarcopenia Muscle. 2018 Feb;9(1):3-19
pubmed: 29151281
Front Cell Dev Biol. 2019 Dec 10;7:323
pubmed: 31921840
Am J Clin Nutr. 1996 Mar;63(3 Suppl):430S-432S
pubmed: 8615335
Biomech Model Mechanobiol. 2012 Mar;11(3-4):461-73
pubmed: 21744269
Life Sci. 2019 Jul 1;228:30-34
pubmed: 31004660
Subcell Biochem. 2019;91:123-159
pubmed: 30888652
World J Urol. 2009 Jun;27(3):363-9
pubmed: 19030866
Mech Ageing Dev. 2019 Jan;177:66-73
pubmed: 29626500
Proc Inst Mech Eng H. 2020 Oct;234(10):1113-1121
pubmed: 32650701
Nat Rev Cardiol. 2018 Sep;15(9):499-500
pubmed: 30065260
Curr Opin Rheumatol. 2003 Sep;15(5):616-22
pubmed: 12960490
Methods Mol Biol. 2017;1627:395-407
pubmed: 28836216
J Orthop Res. 2013 Feb;31(2):315-21
pubmed: 22886741
Anat Sci Educ. 2012 Sep-Oct;5(5):264-72
pubmed: 22573575
Nat Commun. 2019 Jun 21;10(1):2757
pubmed: 31227697
J Biophotonics. 2013 Feb;6(2):129-42
pubmed: 22791562
Rheumatology (Oxford). 2017 Oct 1;56(10):1784-1793
pubmed: 28957567
Int J Mol Sci. 2020 Aug 21;21(17):
pubmed: 32825633
Ann Rheum Dis. 2017 Jun;76(6):1142-1148
pubmed: 28298375
Osteoarthritis Cartilage. 2010 Jul;18(7):876-82
pubmed: 20417297
Biomed Res Int. 2019 Mar 31;2019:6390182
pubmed: 31049352
Exp Gerontol. 2019 Jul 1;121:81-90
pubmed: 30928680
Int J Mol Sci. 2018 Dec 18;19(12):
pubmed: 30567407
Osteoarthritis Cartilage. 2015 Nov;23(11):1966-71
pubmed: 26521742
J Bodyw Mov Ther. 2008 Jul;12(3):198-200
pubmed: 19083675
J Biomed Opt. 2011 Apr;16(4):040502
pubmed: 21529064
Cells. 2020 Jul 13;9(7):
pubmed: 32668663
J Anat. 2019 Jul;235(1):80-87
pubmed: 30945285
Proc Natl Acad Sci U S A. 2020 May 5;117(18):9723-9732
pubmed: 32332170
Rheum Dis Clin North Am. 2004 Nov;30(4):783-97, vii
pubmed: 15488693
J Mol Cell Cardiol. 2015 Jun;83:1-13
pubmed: 25870157
World J Clin Cases. 2019 Aug 26;7(16):2134-2142
pubmed: 31531309
Artery Res. 2013 Jun 1;7(2):73-80
pubmed: 23667404
Nat Rev Dis Primers. 2016 Oct 13;2:16072
pubmed: 27734845
Adv Drug Deliv Rev. 2003 Nov 28;55(12):1531-46
pubmed: 14623400
J Anat. 2018 Aug;233(2):146-154
pubmed: 29761471

Auteurs

Elena Stocco (E)

Department of Neuroscience, Institute of Human Anatomy, University of Padova, Padova, Italy.
L.i.f.e.L.a.b. Program, Consorzio per la Ricerca Sanitaria, Padova, Italy.

Elisa Belluzzi (E)

Orthopedic and Traumatologic Clinic, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy.
Musculoskeletal Pathology and Oncology Laboratory, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy.

Martina Contran (M)

Department of Neuroscience, Institute of Human Anatomy, University of Padova, Padova, Italy.

Rafael Boscolo-Berto (R)

Department of Neuroscience, Institute of Human Anatomy, University of Padova, Padova, Italy.

Edgardo Picardi (E)

Department of Neuroscience, Institute of Human Anatomy, University of Padova, Padova, Italy.

Diego Guidolin (D)

Department of Neuroscience, Institute of Human Anatomy, University of Padova, Padova, Italy.

Chiara Giulia Fontanella (CG)

Centre for Mechanics of Biological Materials, University of Padova, Padova, Italy.
Department of Industrial Engineering, University of Padova, Padova, Italy.

Eleonora Olivotto (E)

RAMSES Laboratory, Research, Innovation & Technology (RIT) Department, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Istituto Ortopedico Rizzoli, Bologna, Italy.

Giuseppe Filardo (G)

Applied and Translational Research Center, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Istituto Ortopedico Rizzoli, Bologna, Italy.

Giulia Borile (G)

L.i.f.e.L.a.b. Program, Consorzio per la Ricerca Sanitaria, Padova, Italy.
Department of Physics and Astronomy "G. Galilei," University of Padova, Padova, Italy.
Institute of Pediatric Research Città della Speranza, Padova, Italy.

Filippo Romanato (F)

L.i.f.e.L.a.b. Program, Consorzio per la Ricerca Sanitaria, Padova, Italy.
Department of Physics and Astronomy "G. Galilei," University of Padova, Padova, Italy.
Institute of Pediatric Research Città della Speranza, Padova, Italy.

Roberta Ramonda (R)

Rheumatology Unit, Department of Medicine, University - Hospital of Padova, Padova, Italy.

Pietro Ruggieri (P)

Orthopedic and Traumatologic Clinic, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy.

Marta Favero (M)

Rheumatology Unit, Department of Medicine, University - Hospital of Padova, Padova, Italy.
Internal Medicine 1, Ca' Foncello Hospital, ULSS2 Marca Trevigiana, Treviso, Italy.

Andrea Porzionato (A)

Department of Neuroscience, Institute of Human Anatomy, University of Padova, Padova, Italy.
L.i.f.e.L.a.b. Program, Consorzio per la Ricerca Sanitaria, Padova, Italy.

Raffaele De Caro (R)

Department of Neuroscience, Institute of Human Anatomy, University of Padova, Padova, Italy.
L.i.f.e.L.a.b. Program, Consorzio per la Ricerca Sanitaria, Padova, Italy.

Veronica Macchi (V)

Department of Neuroscience, Institute of Human Anatomy, University of Padova, Padova, Italy.
L.i.f.e.L.a.b. Program, Consorzio per la Ricerca Sanitaria, Padova, Italy.

Classifications MeSH