Comparative Analysis of Different Local Anesthetic Solutions Available in Market: An In Vitro and Clinical Study.
Journal
European journal of dentistry
ISSN: 1305-7456
Titre abrégé: Eur J Dent
Pays: Germany
ID NLM: 101303672
Informations de publication
Date de publication:
Oct 2021
Oct 2021
Historique:
pubmed:
28
5
2021
medline:
28
5
2021
entrez:
27
5
2021
Statut:
ppublish
Résumé
This study aimed to evaluate and compare various commercially available local anesthetic solutions. A total of 150 commercially available local anesthetic cartridges of similar composition (2% lidocaine with epinephrine 1:100,000) were randomly collected and divided into 3 groups. The designations of groups were selected from their product names such that each group consisted of 60 cartridges. Group S (Septodont, France) Group M (Medicaine, Korea) and Group H (HD-Caine, Pakistan). The samples were divided into five sub-groups, each consisting of 10 cartridges from each group to investigate each parameter. The acquired data was statistically analyzed and compared (using SPSS version 12). Compositional analysis revealed a non-significant (P>0.05) difference when the three Groups were compared with standard lidocaine and epinephrine solutions. The mean pH values of samples from group S, M, and H respectively fell within the range of pH values of commercially available solutions. Non-significant difference in EPT values of Group S and H was found when efficacy was compared ( Within the limitations of these investigations, it appears that the properties of different manufacturers fall within the recommended ranges as mentioned in literature and do not appear to be statistically different in the variables we have tested.
Identifiants
pubmed: 34041728
doi: 10.1055/s-0041-1727553
pmc: PMC8630971
doi:
Types de publication
Journal Article
Langues
eng
Pagination
660-668Informations de copyright
European Journal of Dentistry. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).
Déclaration de conflit d'intérêts
None declared.
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