Impact of atrial fibrillation pattern on outcomes after left atrial appendage closure: lessons from the prospective LAARGE registry.
AF type
Atrial fibrillation
Left atrial appendage closure
Non-paroxysmal AF
Safety outcomes
Journal
Clinical research in cardiology : official journal of the German Cardiac Society
ISSN: 1861-0692
Titre abrégé: Clin Res Cardiol
Pays: Germany
ID NLM: 101264123
Informations de publication
Date de publication:
May 2022
May 2022
Historique:
received:
12
01
2021
accepted:
17
05
2021
pubmed:
28
5
2021
medline:
4
5
2022
entrez:
27
5
2021
Statut:
ppublish
Résumé
Non-paroxysmal (NPAF) forms of atrial fibrillation (AF) have been reported to be associated with an increased risk for systemic embolism or death. Comparison of procedural details and long-term outcomes in patients (pts) with paroxysmal AF (PAF) against controls with NPAF in the prospective, multicentre observational registry of patients undergoing LAAC (LAARGE). A total of 638 pts (PAF 274 pts, NPAF 364 pts) were enrolled. In both groups, a history of PVI was rare (4.0% vs 1.6%, p = 0.066). The total CHA Atrial fibrillation type did not impair periprocedural safety or in-hospital MACE patients undergoing LAAC. However, after one year, NPAF was associated with higher mortality.
Sections du résumé
BACKGROUND
BACKGROUND
Non-paroxysmal (NPAF) forms of atrial fibrillation (AF) have been reported to be associated with an increased risk for systemic embolism or death.
METHODS
METHODS
Comparison of procedural details and long-term outcomes in patients (pts) with paroxysmal AF (PAF) against controls with NPAF in the prospective, multicentre observational registry of patients undergoing LAAC (LAARGE).
RESULTS
RESULTS
A total of 638 pts (PAF 274 pts, NPAF 364 pts) were enrolled. In both groups, a history of PVI was rare (4.0% vs 1.6%, p = 0.066). The total CHA
CONCLUSION
CONCLUSIONS
Atrial fibrillation type did not impair periprocedural safety or in-hospital MACE patients undergoing LAAC. However, after one year, NPAF was associated with higher mortality.
Identifiants
pubmed: 34043052
doi: 10.1007/s00392-021-01874-3
pii: 10.1007/s00392-021-01874-3
pmc: PMC9054864
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
511-521Informations de copyright
© 2021. The Author(s).
Références
Heart Rhythm. 2018 Jan;15(1):3-8
pubmed: 29304951
J Am Coll Cardiol. 2017 Dec 19;70(24):2964-2975
pubmed: 29103847
J Am Coll Cardiol. 2012 Aug 7;60(6):531-8
pubmed: 22858289
Eur Heart J. 2016 Aug;37(31):2478-87
pubmed: 26984861
Eur Heart J. 2015 Feb 1;36(5):288-96
pubmed: 25209598
Europace. 2017 Jan;19(1):4-15
pubmed: 27540038
Circulation. 2014 Feb 25;129(8):837-47
pubmed: 24345399
Cardiol Ther. 2020 Jun;9(1):45-58
pubmed: 31898209
Clin Res Cardiol. 2021 Jan;110(1):12-20
pubmed: 32296971
Stroke. 1991 Aug;22(8):983-8
pubmed: 1866765
Eur Heart J. 2016 May 21;37(20):1591-602
pubmed: 26888184
Clin Res Cardiol. 2021 Jun;110(6):775-788
pubmed: 33089361
J Interv Card Electrophysiol. 2020 Sep;58(3):273-280
pubmed: 31707534
Clin Res Cardiol. 2021 Jun;110(6):831-840
pubmed: 33098470
Heart Rhythm. 2017 Sep;14(9):1302-1308
pubmed: 28577840
Europace. 2019 Aug 31;22(2):184
pubmed: 31504441
N Engl J Med. 2020 Oct 1;383(14):1305-1316
pubmed: 32865375
J Am Coll Cardiol. 2007 Nov 27;50(22):2156-61
pubmed: 18036454
Heart Rhythm. 2016 Sep;13(9):1823-8
pubmed: 27291510
Am J Cardiol. 2020 Sep 15;131:27-32
pubmed: 32753268
Circulation. 2018 May 15;137(20):e623-e644
pubmed: 29661944
Circulation. 2018 Aug 28;138(9):874-885
pubmed: 29752398
Clin Res Cardiol. 2015 Jun;104(6):463-70
pubmed: 25537233
Eur Heart J. 2021 Feb 1;42(5):373-498
pubmed: 32860505
JACC Cardiovasc Interv. 2019 Jun 10;12(11):1003-1014
pubmed: 31103540
JACC Cardiovasc Interv. 2019 Jun 10;12(11):1018-1026
pubmed: 31171276