Alginate-chitosan oligosaccharide-ZnO composite hydrogel for accelerating wound healing.
Alginates
/ chemistry
Animals
Anti-Infective Agents
/ chemistry
Bacillus subtilis
/ drug effects
Candida albicans
/ drug effects
Cell Line
Chitin
/ analogs & derivatives
Chitosan
Escherichia coli
/ drug effects
Hemolysis
/ drug effects
Humans
Hydrogels
/ chemistry
Male
Mice
Microbial Sensitivity Tests
Nanoparticles
/ chemistry
Oligosaccharides
Polysaccharides
/ chemistry
Porosity
Rats, Sprague-Dawley
Staphylococcus aureus
/ drug effects
Wound Healing
/ drug effects
Zinc Oxide
/ chemistry
Alginate
Chitosan oligosaccharide
Hydrogel
Wound healing
Zinc oxide
Journal
Carbohydrate polymers
ISSN: 1879-1344
Titre abrégé: Carbohydr Polym
Pays: England
ID NLM: 8307156
Informations de publication
Date de publication:
15 Aug 2021
15 Aug 2021
Historique:
received:
09
02
2021
revised:
07
04
2021
accepted:
16
04
2021
entrez:
28
5
2021
pubmed:
29
5
2021
medline:
16
10
2021
Statut:
ppublish
Résumé
Moist, breathable and antibacterial microenvironment can promote cell proliferation and migration, which is beneficial to wound healing. Here, we fabricated a novel sodium alginate-chitosan oligosaccharide‑zinc oxide (SA-COS-ZnO) composite hydrogel by spontaneous Schiff base reaction, using aldehydated sodium alginate (SA), chitosan oligosaccharide (COS), and zinc oxide (ZnO) nanoparticles, which can provide a moist and antibacterial environment for wound healing. The porosity and swelling degree of SA-COS-ZnO hydrogel are 80% and 150%, respectively, and its water vapor permeability is 682 g/m
Identifiants
pubmed: 34044919
pii: S0144-8617(21)00487-2
doi: 10.1016/j.carbpol.2021.118100
pii:
doi:
Substances chimiques
Alginates
0
Anti-Infective Agents
0
Hydrogels
0
Oligosaccharides
0
Polysaccharides
0
oligochitosan
0
Chitin
1398-61-4
Chitosan
9012-76-4
Zinc Oxide
SOI2LOH54Z
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
118100Informations de copyright
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