Framingham Heart Study: JACC Focus Seminar, 1/8.
Framingham Heart Study
cardiovascular epidemiology
molecular epidemiology
risk factors
Journal
Journal of the American College of Cardiology
ISSN: 1558-3597
Titre abrégé: J Am Coll Cardiol
Pays: United States
ID NLM: 8301365
Informations de publication
Date de publication:
01 06 2021
01 06 2021
Historique:
received:
14
10
2020
revised:
04
01
2021
accepted:
20
01
2021
entrez:
28
5
2021
pubmed:
29
5
2021
medline:
20
11
2021
Statut:
ppublish
Résumé
The Framingham Heart Study is the longest-running cardiovascular epidemiological study, starting in 1948. This paper gives an overview of the various cohorts, collected data, and most important research findings to date. In brief, the Framingham Heart Study, funded by the National Institutes of Health and managed by Boston University, spans 3 generations of well phenotyped White persons and 2 cohorts comprised of racial and ethnic minority groups. These cohorts are densely phenotyped, with extensive longitudinal follow-up, and they continue to provide us with important information on human cardiovascular and noncardiovascular physiology over the lifespan, as well as to identify major risk factors for cardiovascular disease. This paper also summarizes some of the more recent progress in molecular epidemiology and discusses the future of the study.
Identifiants
pubmed: 34045026
pii: S0735-1097(21)01096-2
doi: 10.1016/j.jacc.2021.01.059
pii:
doi:
Types de publication
Historical Article
Journal Article
Research Support, N.I.H., Extramural
Research Support, N.I.H., Intramural
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
2680-2692Subventions
Organisme : NHLBI NIH HHS
ID : R03 HL145195
Pays : United States
Organisme : NHLBI NIH HHS
ID : 75N92019D00031
Pays : United States
Organisme : NHLBI NIH HHS
ID : HHSN268201500001I
Pays : United States
Organisme : NHLBI NIH HHS
ID : N01 HC025195
Pays : United States
Informations de copyright
Copyright © 2021. Published by Elsevier Inc.
Déclaration de conflit d'intérêts
Funding Support and Author Disclosures Dr. Nayor is supported by the National Heart, Lung, and Blood Institute (K23-HL138260). Dr. Tsao is supported by the National Institutes of Health (5R03-HL145195). Dr. Levy is supported by the Division of Intramural Research of the National Heart, Lung, and Blood Institute of the National Institutes of Health. Dr. Vasan is supported in part by the Evans Medical Foundation and the Jay and Louis Coffman Endowment from the Department of Medicine, Boston University School of Medicine. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.