A Case of Refractory Esophageal Ulcer Caused by Radiotherapy for Hepatocellular Carcinoma.
Chronic esophageal toxicity
Esophageal stenosis
Esophageal ulcer
Hepatocellular carcinoma
Radiotherapy
Journal
World journal of oncology
ISSN: 1920-454X
Titre abrégé: World J Oncol
Pays: Canada
ID NLM: 101564097
Informations de publication
Date de publication:
Jun 2021
Jun 2021
Historique:
received:
08
03
2021
accepted:
15
04
2021
entrez:
28
5
2021
pubmed:
29
5
2021
medline:
29
5
2021
Statut:
ppublish
Résumé
A 77-year-old man who underwent radiotherapy for hepatocellular carcinoma 6 months prior consulted for esophageal obstruction. Esophagogastroduodenoscopy revealed an esophageal ulcer caused by radiotherapy for hepatocellular carcinoma. He was treated with dietary counseling and vonoprazan. After 9 months, the ulcer improved but a moderate stenosis remained. Several factors such as high fraction size, history of chemotherapy, and stress associated with food intake might involve in the development of a radiation-associated ulcer. Opportunities to choose radiotherapy for hepatocellular carcinoma may increase, so we hypothesize that esophageal ulcers might be a complication that should be noted associated with this therapy.
Identifiants
pubmed: 34046101
doi: 10.14740/wjon1370
pmc: PMC8139740
doi:
Types de publication
Case Reports
Langues
eng
Pagination
67-72Informations de copyright
Copyright 2021, Hamada et al.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
Références
Cancer. 1999 Jul 15;86(2):220-8
pubmed: 10421257
Indian J Cancer. 2004 Apr-Jun;41(2):81-4
pubmed: 15318013
Radiother Oncol. 2010 Oct;97(1):48-53
pubmed: 20832884
Radiother Oncol. 1990 Oct;19(2):121-9
pubmed: 2255769
Surg Endosc. 2012 Oct;26(10):2877-83
pubmed: 22543993
Int J Radiat Oncol Biol Phys. 2008 Dec 1;72(5):1378-84
pubmed: 18501528
Int J Radiat Oncol Biol Phys. 1991 May 15;21(1):109-22
pubmed: 2032882
Cancer. 2020 Jan 15;126(2):363-372
pubmed: 31747476
Clin Lung Cancer. 2011 Jul;12(4):245-51
pubmed: 21726824
Int J Radiat Oncol Biol Phys. 1999 Feb 1;43(3):525-30
pubmed: 10078632
Int J Radiat Oncol Biol Phys. 2013 Sep 1;87(1):73-80
pubmed: 23920388
Radiother Oncol. 2012 Feb;102(2):303-8
pubmed: 21885139
Cancer. 2006 Apr 15;106(8):1653-63
pubmed: 16541431
Esophagus. 2019 Jan;16(1):25-43
pubmed: 30171414
Int J Clin Oncol. 2012 Jun;17(3):263-71
pubmed: 21748259
Auris Nasus Larynx. 2009 Aug;36(4):505-8
pubmed: 19117708
World J Gastroenterol. 2015 Dec 14;21(46):13101-12
pubmed: 26673627
Cancer. 1991 May 1;67(9):2258-61
pubmed: 1707338
Arch Intern Med. 1985 Aug;145(8):1443-6
pubmed: 4026476
Hepatol Int. 2017 Jul;11(4):317-370
pubmed: 28620797
Cancer. 2003 Apr 1;97(7):1693-700
pubmed: 12655526
Int J Radiat Oncol Biol Phys. 2014 Apr 1;88(5):1041-7
pubmed: 24661657
Surg Case Rep. 2020 Jun 16;6(1):138
pubmed: 32548687
Cancer. 1993 Jul 15;72(2):405-9
pubmed: 8391378
Cancer. 2012 Nov 1;118(21):5424-31
pubmed: 22570179